Causes of high alkaline phosphatase in pregnant women

Pregnant women need to go to the hospital regularly for detailed physical examinations after pregnancy, so that they can know their physical condition. If the alkaline phosphatase is high, they will be very nervous. In fact, such a single symptom cannot represent any situation, so you still have to consult your doctor to make the next treatment plan. Do not use drugs indiscriminately. Let us understand the causes of alkaline phosphatase in pregnant women.

During pregnancy, the fetus grows day by day in the uterus, and all the fetus's breathing and excretion are completely dependent on the mother. Therefore, the metabolism of the pregnant woman is enhanced and the burden on the liver increases. Therefore, in normal pregnant women, some liver functions will change and alkaline phosphatase will also increase.

Because the metabolism of pregnant women increases during pregnancy, the functions of the fetus in the uterine cavity such as breathing and excretion are all completed by the mother, the glycogen metabolism in the liver of pregnant women is enhanced, and the burden on the liver is increased. In some normal pregnant women, some liver function tests will also show slight changes, such as increased blood cholesterol and alkaline phosphatase, which shows that normal pregnancy has a certain degree of impact on liver function.

Alkali phosphatase is widely distributed in human tissues such as bones, liver, intestines, and placenta. It is mainly used for the examination of obstructive jaundice, primary liver cancer, secondary liver cancer, and cholestatic hepatitis. In patients with these diseases, liver cells overproduce ALP, which enters the blood through the lymphatic tract and hepatic sinusoids. At the same time, due to the obstruction of bile excretion in the intrahepatic bile duct, bile refluxes into the blood, causing a significant increase in serum alkaline phosphatase.

However, since this enzyme is also very active in bone tissue, serum alkaline phosphatase may also increase in pregnant women, during the fracture healing period, in patients with osteomalacia, rickets, osteocellular carcinoma, osteoporosis, liver abscess, liver tuberculosis, cirrhosis, leukemia, and hyperthyroidism, and should be differentiated. A single abnormality does not mean anything, and a low level of alkaline phosphatase does not have much significance. No need to take medicine. There won't be anything right.

In this case, it is possible that the pregnant woman's alkaline phosphatase is physiologically elevated. Since the alkaline phosphatase in the bone tissue is highly active during pregnancy, the elevated level will appear. This has no effect on the fetus. It is recommended that you observe the situation for the time being. If you feel any discomfort, you'd better have a detailed examination and take medication under the guidance of a doctor.

In the above article, let us understand the reasons why alkaline phosphatase is high in pregnant women. If the examination shows that the level is not very high, it will have no effect on the fetus and no treatment is needed. If symptoms of discomfort have already appeared, medication should be used.