What is cervical cytology test

When some patients go to the hospital for examination and treatment of cervical problems, the doctor will show them a cervical cytology test strip. So what is cervical cytology? To be honest, I think this is a very new word. Do you know anything about it? If you don’t know much about it like me, let’s take a look at what doctors tell us about cervical cytology.

TCT examination uses a liquid-based thin-layer cell detection system to detect cervical cells and perform cytological classification diagnosis. It is currently the most advanced cervical cancer cell cytological examination technology in the world. The following are the terms on the report and their meanings: Atypical squamous cells of undetermined significance (ASC-US) Squamous epithelial cells have nuclei larger than normal but insufficient to diagnose low-grade lesions. They also include atypical parakeratotic cells, atypical metaplastic cells, and atypical repair cells. This diagnosis includes a variety of situations. The pathologist will explain and make suggestions based on the patient's specific situation, such as follow-up examination after 3 to 6 months, follow-up examination after the inflammation subsides, and colposcopy-based cervical or endometrial biopsy. If conditions permit, it is best to conduct a DNA test for high-risk HPV types.

Atypical squamous cells, high-grade lesions cannot be excluded (ASC-H) The squamous cells are atypical, with small cells in piles and loss of nuclear polarity, and high-grade lesions cannot be excluded. When diagnosing ASC-H, DNA testing for high-risk HPV is necessary, and colposcopic biopsy is also recommended. It is incorrect to treat the patient directly without a biopsy. Low-grade lesions (LSIL) are equivalent to mild atypical hyperplasia of cervical squamous epithelium (CINⅠ), including HPV infection. The early treatment measure is to perform a colposcopy biopsy and a DNA test for high-risk HPV types. There is evidence that HPV infection is a major risk factor for disease progression.

High-grade lesions (HSIL) include moderate cervical squamous cell hyperplasia (CINⅡ), severe cervical squamous cell hyperplasia (CINⅢ) and carcinoma in situ. It is unquestionable that this type of patient should undergo colposcopy as soon as possible. Squamous cell carcinoma should be confirmed by colposcopy and biopsy. Atypical glandular cells (AGC) The pathologist will try to distinguish whether these cells are from the endocervical or endometrial origin. At the same time, the placement of an intrauterine contraceptive device, polyps, and some benign lesions can cause various changes in the morphology of glandular cells. Even excessive force during sampling can cause large pieces of glandular cells to fall off, which can also create the illusion that the glandular cells are typical. The necessary medical history should be provided at this time, and a follow-up examination or biopsy can be performed, especially a biopsy of the cervical canal and endometrium.

Atypical glandular cells, prone to neoplasia (AGC-N) The pathological diagnosis of adenocarcinoma in situ and adenocarcinoma is relatively difficult and is often classified as this type when insufficient evidence is available. Therefore, a biopsy is necessary. Adenocarcinoma in situ and adenocarcinoma should be confirmed by endocervical and endometrial biopsy. It is worth emphasizing that although TCT is a simple, non-invasive, economical and repeatable detection method, it is only a preliminary screening after all. The experimental methods and steps determine that it is impossible to observe all cell preparations; at the same time, morphological observation is subjective to a certain extent, and false positive and false negative results are inevitable. The true diagnosis should still rely on biopsy.

The above content is the introduction given to us by the doctor about cervical exfoliated cytology examination. So, do you know about cervical exfoliated cytology examination? I think you know a little bit about it. If you want to know more, you can communicate with our online doctors. Our hospital has arranged professional doctors to take turns online 24 hours a day. I believe they can answer your questions.