What is the cause of ovarian failure?

Uterine and ovarian anovulation is a key cause of infertility, with a prevalence rate of 25% to 30%, which has caused great confusion for some women who are preparing for pregnancy. So what is the reason for the lack of ovulation in the uterus and ovaries? What is the reason for the lack of ovulation in the uterus and ovaries? Let’s have a simple understanding and understanding of this issue below. I hope the following points will be of some help to everyone!

What is anovulation? First, let's discuss what ovulation is: ovulation refers to the period when the mature follicle develops to a certain stage and is prominently protruding from the surface of the uterus and ovary. Along with the rapid increase of egg fluid and the increase of air pressure, the protruding part of the uterus and ovary tissue becomes thinner and thinner, and finally breaks apart. The secondary coil oocyte, the zona pellucida and the corona radiata are discharged from the uterus and ovary along with the egg fluid. This period is called ovulation.

From the definition of ovulation, we know that anovulation refers to the situation that the egg cannot be discharged from the ovary normally or no egg develops. The symptoms of anovulation are mainly reflected in women's unique characteristics such as growth and development status, menstruation, and secretions.

The causes of uterine and ovarian anovulation include polycystic ovary syndrome, premature ovarian failure, ovarian absenteeism, Turner syndrome, simple sex hormone dysplasia, chromosomal abnormalities, etc. To sum up, there are several reasons as follows:

1. Hypothalamic-pituitary-pituitary-ovarian axis dysfunction causes anovulatory menstruation and amenorrhea.

Mental factors such as tension or excessive anxiety, anger, sadness and other negative emotions can lead to an imbalance in head function, resulting in anovulation or abnormal ovulation period, or anovulation due to Sheehan's syndrome or hyperlactosis.

2. Systemic diseases

For example, moderate to severe malnutrition or lack of some important nutrients in the diet can affect ovarian infertility. Chronic diseases, genetic metabolic diseases such as low or hyperthyroidism, diabetes, adrenergic nerve dysfunction, etc. can also cause infertility.

3. Medicines

Taking some drugs, such as high-potency steroid injections of emergency contraception, disrupts the interaction between the brain and the ovaries, inhibiting ovulation and thus preventing pregnancy. There are signs that the longer this type of contraceptive is used, the higher the likelihood of amenorrhea.

4. Uterine and ovarian diseases

Including congenital uterine and ovarian dysplasia, polycystic ovarian syndrome, ovarian aging, uterine and ovarian tumors, etc.

5. Poor development of the uterus.

Poor uterine development can cause anovulation. Blockage of the fallopian tubes can also cause the egg to be expelled.

Female ovarian anovulation is a common endocrine disease, but one should not seek medical treatment indiscriminately or use ovulation-inducing drugs at will. If a woman suffers from anovulation, she should go to a reliable hospital for a thorough examination, identify the cause, and treat it with medication.