Normal value of glycosylated hemoglobin in pregnant women

When women are pregnant, they need to have prenatal checkups almost every month. Sometimes they need to draw several tubes of blood for different tests. What is the normal value of glycosylated hemoglobin for pregnant women? Under normal circumstances, the glycosylated hemoglobin of pregnant women is between 4% and 6%. If the glycosylated hemoglobin is higher than 9%, gestational diabetes, cataracts, etc. may occur. The following is a detailed introduction to the impact of glycated hemoglobin on pregnant women.

1. Indicators that reflect the overall blood sugar control of diabetic patients

The normal value of glycosylated hemoglobin is 4%-6%. < 6% is under-controlled and hypoglycemia is likely to occur; 6%-7% is ideal control; 7%-8% is acceptable; 8%-9% is poor control; > 9% is poor control, which is a risk factor for the occurrence and development of chronic complications, and may cause acute complications such as ketoacidosis, so when it is > 8%, blood sugar control should be strengthened.

2. Helps to understand chronic complications of diabetes

If the glycated hemoglobin is > 9%, it means that the patient has persistent hyperglycemia, which may lead to complications such as diabetic nephropathy, arteriosclerosis, and cataracts. It is also a high-risk factor for death from myocardial infarction and stroke. Chen Xiaozhuan et al. reported that the increase of glycosylated hemoglobin is related to the occurrence, development and prognosis of ischemic cerebral infarction. The level of glycosylated hemoglobin in patients with diabetic nephropathy is higher than that in patients without diabetic nephropathy, and as the level of glycosylated hemoglobin increases, the levels of urine glucose lb, IgG, and NAG increase accordingly.

3. Guide the adjustment of blood sugar

When glycosylated hemoglobin is < 7.3%, postprandial blood glucose has a greater impact on the level of glycosylated hemoglobin; when it is between 7.3% and 8.4%, fasting and postprandial blood glucose have similar effects on glycosylated hemoglobin; when it is > 8.5%, fasting blood glucose plays a more important role. Therefore, people with high levels of glycosylated hemoglobin need better control of fasting blood glucose levels. Therefore, those with glycosylated hemoglobin between 7% and 8% should intervene more in postprandial blood sugar to reduce hypoglycemia reactions; those with > 8% should consider both fasting and postprandial blood sugar; and those with < 8% should focus on improving postprandial blood sugar.

In addition, since glycosylated hemoglobin reflects the average level over a period of time, such as 6% to 7% measured regularly, but this time it is > 8%, it means that the previous treatment plan cannot control blood sugar well and a new treatment plan needs to be adjusted.

4. It is of certain significance in judging the different stages of diabetes

The average glycosylated hemoglobin level in patients with normal glucose tolerance was 5.6%, the average level in patients with elevated fasting blood glucose was 6.2%, the average level in patients with impaired glucose tolerance was 5.9%, the average level in patients with both impaired glucose tolerance and elevated fasting blood glucose was 62%, and the average level in newly screened diabetic patients was 8%. Therefore, the level of glycosylated hemoglobin can represent the conditions of different stages of prediabetes and diabetic patients.

5. The significance of distinguishing stress-induced hyperglycemia and testing in gestational diabetes. Blood glucose increases under stress conditions such as cerebrovascular emergencies, but glycosylated hemoglobin does not increase. It is not enough to just measure blood sugar for gestational diabetes. It is more meaningful to control glycosylated hemoglobin to < 8% to avoid macrosomia, stillbirth, malformation, and pre-term pain. Therefore, glucose-containing hemoglobin is an important parameter for the control of gestational diabetes.