Congenital immature uterus without menstruation

Women's special physiological period is regular, and ovulation will occur after each menstruation. However, if a woman suffers from congenital uterine immaturity and has no menstruation, infertility will occur. If a woman reaches a certain age and has not had her period and the second symptom is not obvious, it is best to seek medical treatment in time. Without menstruation, ovulation may not occur, making pregnancy more difficult.

Clinical manifestations

Delayed menarche accompanied by oligomenorrhea, dysmenorrhea, or even amenorrhea is often an important clinical manifestation of uterine dysplasia. It is necessary to understand the size of the uterus and whether other endocrine systems are normal, whether there are abnormalities or dysfunctions in organs such as the hypothalamus, pituitary gland, ovaries, whether there are ovulation disorders, and whether the basic conditions for fertility are met. Under normal circumstances, when a woman matures, her uterus naturally becomes capable of reproduction. If abnormalities occur in organs such as the pituitary gland, hypothalamus, and ovaries, leading to endocrine dysfunction, uterine development will be slow, and other secondary sexual characteristics will inevitably be affected, which can lead to infertility.

When women reach the age of sexual development, their menstruation is delayed or infrequent, their breasts do not show obvious swelling, their pubic hair is sparse, and even when their menstruation comes, the amount is very small, this situation should be viewed with caution.

Disease hazards

"Small uterus" is one of the main reasons for infertility patients to seek medical treatment clinically. Some gynecologists rashly diagnose patients as having a small uterus and being unfavorable for conception based solely on internal examination or B-ultrasound measurement. Many female patients have shouldered a heavy psychological burden because of the "diagnosis" made by these doctors. They believe that their uterus is small and they cannot conceive. Some families have even broken up because of this. A small uterus alone is not necessarily the direct cause of infertility. Infertility will only occur if the ovaries are also underdeveloped.

The above deformities cause the uterus to be unable to store and transport semen and sperm normally, making it impossible to obtain sperm and conceive; the uterine morphology and volume are abnormal, and the myometrium is underdeveloped, which is not conducive to the implantation of the fertilized egg, implantation and embryonic development, and can easily lead to early pregnancy miscarriage, abnormal placental position, fetal growth retardation, etc.

Specific hazards

1. Infertility

Many people who have no uterus, primordial uterus, or immature uterus seek medical treatment for infertility.

2. Abnormal menstruation

Those with a primordial uterus or no uterus generally present with primary amenorrhea. A young uterus may produce scant menstrual flow. In patients with double uterus, bicornuate uterus and duplicate uterus, menorrhagia or prolonged menstruation may occur due to the increase in endometrial area. A rudimentary horn of the uterus may cause periodic lower abdominal pain due to uterine hematoma, and the enlarged rudimentary horn can easily be mistaken for an ovarian cyst.

3. Pathological pregnancy

Complications are also very likely to occur during pregnancy, such as the fertilized egg implanting on the underdeveloped uterine wall or mediastinum, affecting the development of the embryo. These can lead to early miscarriage, habitual miscarriage, premature birth, etc. If the fertilized egg implants in the rudimentary horn of the uterus, it will usually rupture during the 4th to 5th month of pregnancy. In the late stages of pregnancy, abnormal fetal presentations such as breech presentation, transverse presentation, and oblique presentation are prone to occur in patients with a bicornuate uterus, unicornuate uterus, or saddle uterus, leading to dystocia.

4. Intrapartum and postpartum pathology

An abnormally developed uterus is often accompanied by uterine muscle hypoplasia, which can easily lead to dystocia, and spontaneous uterine rupture can usually be seen. Placental retention and postpartum uterine atony bleeding are common after delivery. Didelphic uterus, bicornuate uterus and uterus with septate uterus can lead to postpartum bleeding, etc.

Treatment options

1. Hormone therapy

Take 1 mg of diethylstilbestrol for 20 consecutive days starting from the 5th day of the menstrual cycle, and stop taking it 5-7 days before menstruation occurs. Continue taking it on the 5th day after the next menstruation, and take it for 3-6 months. After the uterus becomes larger, give an appropriate amount of progesterone in the second half of the menstruation for a total of 3 months to stimulate the corpus luteum function and facilitate conception. Sequential estrogen-progestin therapy can also be used.

2. Surgery

On the basis of hormone therapy to enlarge the uterus, adding cervical dilation surgery and endometrial curettage can obtain or increase the chance of conception.

3. Traditional Chinese medicine treatment

You can take placenta tablets and inject placental tissue fluid. Chinese patent medicines such as Wu Ji Bai Feng Wan can be taken under the guidance of a doctor. Other ingredients include 500 grams each of deer antler cream, placenta, cnidium monnieri, callicarpa ovata, cistanche deserticola, raspberry, angelica sinensis, and glossy privet fruit, 25 grams of pearl, and 100 grams of purple quartz. Grind into fine powder and pass through a 120-mesh sieve. Take 10 grams each time, 3 times a day, swallow. One course of treatment is 3 months, and the maximum number of courses is 3.

Prevention methods

1. Pay attention to developing good living habits, eat regularly, do not overeat, do not be picky or partial eaters, and pay attention to a reasonable combination of nutrition. During the growth period, do not blindly diet to lose weight, especially for thin girls during the growth period.

2. Pay attention to the combination of work and rest, actively participate in physical exercise, maintain adequate sleep, and do not blindly diet to lose weight, because fat is an essential substance for the production of various hormones, especially sex hormones, so if women have less fat content in their bodies, it is also extremely detrimental to their health.

3. Girls in puberty should be careful not to go on a blind diet to lose weight, especially those thin girls in their puberty period, because the amount of fat intake in the body will directly affect the level of female estrogen. If estrogen levels are not normal, the development of the reproductive organs will be affected and uterine hypoplasia may occur.

4. For women with abnormal uterine development, if there are no obvious clinical symptoms, no special treatment measures may be taken. However, if uterine hypoplasia causes dysmenorrhea, amenorrhea, etc., endocrine therapy can be tried. If drug treatment does not achieve therapeutic effect, surgical treatment may be considered.

Conclusion: After reading the above content, I believe everyone has a certain understanding of the disease of immature uterus. The occurrence of immature uterus will have a great impact on the entire family. When this disease is discovered, it must be treated in time. In daily life, we should also pay attention to exercise and combine work and rest to ensure good health.