How is vulvar leukoplakia caused?

Women are often troubled by various gynecological diseases due to the characteristics of their vagina. Among them, vulvar leukoplakia is one of the common diseases. In recent years, the incidence of this disease has been on the rise clinically, and the age range of onset is also relatively wide. Women can develop the disease at any age, starting from childhood, especially around 50 years old. Some have a short course of illness, while others last for decades. The main symptom is vulvar itching, which is sometimes extremely itchy and accompanied by local burning pain. If the itching is not treated for a long time, local ulcers, cracks and even infections may occur. If you have this disease, your vulva will shrink significantly, your labia majora will have thick lines and rough skin, and in severe cases it may even cause difficulty in urination and affect your sexual life. So, let us focus on the causes of vulvar leukoplakia.

1. Genetic inheritance

The occurrence of vulvar leukoplakia is not age-limited and may occur at all ages. There have been cases in childhood, adolescence, menopause and old age, but most of them are middle-aged and elderly people. For those patients who have symptoms in childhood, it is very likely caused by genetic inheritance, and the vulvar leukoplakia caused by genetics is mainly atrophic type.

2. Genital infection and inflammatory stimulation:

Vulvar infection mainly refers to the patient's unhygienic living habits, such as not regularly using PH4 weak acid formula feminine care liquid to clean the vulva; the habit of wearing synthetic underwear instead of pure cotton underwear; unclean sanitary products; bathing in a bathhouse or swimming in a bathhouse that does not meet sanitary conditions, etc. Vulvar infection and inflammatory stimulation are the main causes of vulvar leukoplakia. 50% or even more patients suffer from this disease. Vulvar infection is related to whether the daily living habits are healthy, and inflammatory stimulation is mainly caused by Trichomonas vaginitis, candidal vaginitis, cervical erosion and other inflammations, which cause increased vulvar secretions and leucorrhea degeneration, and long-term irritation to the vulva, causing vulvar leukoplakia.

3. Endocrine disorders:

The human body's fluid regulation system, also known as the endocrine system. The occurrence of many diseases is inseparable from the influence of the endocrine system. If the endocrine system mutates, diseases are likely to occur. Through the determination of tritium-labeled thymidine, it is believed that there is a tissue-specific protein hormone in the dermis that can inhibit the division and growth of epidermal cells and only acts locally on the epidermis. It is called inhibitory hormone. The production of inhibin is a factor that leads to the occurrence of vulvar leukoplakia. It causes an imbalance between the proliferation of local connective tissue and the stimulation of epidermal metabolism, leading to vulvar leukoplakia.

4. Traumatic impact:

Many pregnant women choose to give birth naturally. At this time, perineal tears may occur, which can easily cause local nerve and blood vessel damage to the pregnant woman. A small number of women may develop vulvar leukoplakia due to this type of trauma.

5. Caused by low immunity or other diseases:

Vulvar leukoplakia has a certain relationship with human immunity, and other diseases also often cause vulvar leukoplakia, the most common of which are diabetes, vitiligo, uterine fibroids, irregular menstruation, etc.