Several friends asked Huazi, "I heard that there is a hypertension vaccine now. Does that mean that hypertension can be cured?" Is acupuncture for hypertension more effective than oral antihypertensive drugs? Huazi said that there is indeed a hypertension vaccine now. The 8th edition of "Pharmacology" has stated that the hypertension vaccine CYT006-AngQb is safe and effective in treating hypertension. However, this conclusion has only been preliminarily confirmed in clinical trials, and it will take some time before the hypertension vaccine can be marketed. 1. What is the hypertension vaccine? The hypertension vaccine is different from ordinary vaccines. The influenza vaccine and hepatitis B vaccine we are familiar with are vaccines for preventing diseases and are injected into healthy people. The hypertension vaccine, on the other hand, is a vaccine for treating diseases and can only be injected into people who already have hypertension, and cannot be used to prevent hypertension in healthy people. The mechanism of the hypertension vaccine is to induce the body's immune system to produce angiotensin antibodies, inhibiting the action of angiotensin, thereby producing a blood pressure lowering effect. Judging from the current experimental results, the effect of the hypertension vaccine is not permanent, and the effect of each injection can only last for a few months, and continuous injections are required to maintain the blood pressure lowering effect. Second, it is not completely free from oral medications. The target of the hypertension vaccine is very single, and the antibodies produced can only inhibit the action of angiotensin. In terms of the antihypertensive mechanism, the hypertension vaccine has a similar effect to pril drugs (angiotensin converting enzyme inhibitors) and sartan drugs (angiotensin 2 receptor antagonists). If the hypertension is not serious, people who take a single medication may not need to continue taking oral medications after using the hypertension vaccine. However, 70% of hypertensive patients cannot fully control their hypertension with only one antihypertensive drug, and need to use multiple antihypertensive drugs in combination. The hypertension vaccine can only replace the effects of "pril" or "sartan". People who need to use diazepam, lolamine, diuretics and other drugs in combination still cannot stop taking the drugs and need to take other oral medications regularly. 3. What is the significance of the hypertension vaccine? Some people may wonder, since the hypertension vaccine cannot solve hypertension once and for all, and its mechanism is similar to that of "pril" and "sartan", and oral medications cannot be completely stopped, then what is the point of developing this vaccine? The significance of hypertension vaccine is that it can improve patient compliance. Hypertension is the most common chronic disease in the world, and hundreds of millions of people need to take medication for a long time to control their blood pressure. During treatment, the biggest reason for treatment failure is not that antihypertensive drugs are ineffective, but that patients find it difficult to take medication regularly. In other words, many hypertensive patients fail to take treatment because they forget to take their medication. The hypertension vaccine, which only needs to be injected once every few months, greatly improves patient compliance. Fourth, both lifestyle intervention and drug treatment are essential. The development of a hypertension vaccine has been proposed since the 1950s. The earliest research on a hypertension vaccine in China was reported in 2012. The development of a hypertension vaccine is a long process, and it is estimated to take at least 10 years. Therefore, the most optimistic estimate is that relevant results will be seen in 2022. However, even with a hypertension vaccine, it is only an additional treatment method to control angiotensin. For most hypertension control, it is still necessary to use multiple drugs in combination with lifestyle interventions. It cannot achieve the effect of not having to take medicine after a shot, nor can it cure hypertension. However, many new antihypertensive drugs are also being developed simultaneously. For example, vasoactive peptide inhibitors, aldosterone synthase inhibitors, soluble epoxide hydrolase inhibitors, natriuretic peptide agonists, vasoactive intestinal peptide type 2 receptor agonists, and mineralocorticoid receptor antagonists all have products undergoing phase 2 and phase 3 clinical trials. I believe that in the near future, humans will have more weapons to treat high blood pressure. At this stage, following the doctor's advice to take medication regularly, eat less salt, control weight, and exercise more are still the best ways to control blood pressure. To sum up, the hypertension vaccine is still in the trial stage, and there is no mature product on the market. It is a therapeutic vaccine that can only be used for people who already have hypertension, but it cannot cure hypertension once and for all. At present, the most effective way to treat hypertension is to use antihypertensive drugs under the guidance of a doctor. If you have any questions about medication, please consult a doctor or pharmacist. I am pharmacist Huazi, welcome to follow me and share more health knowledge. |
<<: How to choose water chestnuts? Why do water chestnuts smell so bad?
I recently read about the psychology of colors th...
Tai Chi is a martial arts sport that conforms to ...
We all know that spare ribs are a common food. Th...
Belly band is a good helper for postpartum mother...
At the beginning of pregnancy, many expectant mot...
Nasal congestion, nasal itching, sneezing, runny ...
Many women experience back pain during ovulation....
Pregnancy test sticks are a product that has emer...
Women who have given birth know that lochia needs...
With the arrival of autumn and winter, influenza ...
We all know that the HPV vaccine has been very po...
Menstruation is a sign of the maturation of a wom...
Women will experience some symptoms in the early ...
Since the 21st century, human society has develop...
Many women in menopause have their periods again ...