Which types of HPV are safe

HPV infection is mainly transmitted through sexual intercourse, and the infection rate depends mainly on the age of the group and the characteristics of their sexual life. The HPV infection rate is highest among young sexually active women, with the peak infection period being around 20 years old. Women who have a normal sexual life have an 80% chance of being infected with at least one type of HPV in their lifetime, but most of them will disappear automatically in a short time.

Currently, WHO/IARC has established 13 high-risk HPV types, including HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 68.

According to scientific research literature in my country, the risk of cervical precancerous lesions and cervical cancer in women with high-risk HPV positive test is 250 times that of negative test subjects. Persistent infection with high-risk HPV can effectively predict the risk of cervical intraepithelial neoplasia grade 2 and above (CIN2). Women who were positive for high-risk HPV had a 167 times greater risk of developing CIN2 than women who were negative.

A national multi-center study conducted in 19 hospitals in seven war zones in China showed that HPV16 was the most common type in cervical squamous cell carcinoma patients (76.6%), followed by HPV18 (7.9%). The infection rates of HPV16 and 18 in cervical adenocarcinoma were 33.65% and 28.86%, respectively. Therefore, HPV16 and 18 are associated with the vast majority of cervical precancerous lesions.

However, more than 90% of high-risk HPV infections can be eliminated by the body's own immune system. However, a very small number of women cannot eliminate the HPV and develop into persistent infection, which in turn develops into cervical precancerous lesions or even cervical cancer. This also indicates that high-risk HPV infection is a necessary cause of cervical cancer.

In the process of cervical lesions, in addition to high-risk HPV infection as the main factor, there are other endogenous and exogenous factors that promote the persistence of high-risk HPV infection and then progress to cervical cancer.

What HPV models and specifications are safe

High-risk HPV infection is completely unsafe. Clinically, if the infection persists, it may cause degeneration of cervical epithelial cells, lead to cervical precancerous lesions, and even develop into cervical cancer. In particular, infection with HPV16 and HPV18 is the main cause of cervical cancer in Asian women. Therefore, in clinical medicine, if high-risk HPV infection is found, a colposcopy should be performed as soon as possible. The main purpose is to determine whether the cervical epithelial cells have become diseased through colposcopy, and then actively provide treatment based on the results. It is recommended that women have a gynecological examination every year and undergo cervical cancer screening. Low-risk HPV infection, except for HPV6 and HPV11 infection, other low-risk infections are relatively safe in clinical medicine. In clinical medicine, infection with HPV6 and HPV11 causes genital warts, which is a type of sexually transmitted disease, mainly caused by a history of high-risk sexual activity.