Will the follicles grow after the night injection?

Oocytes are a prerequisite for the development of life. Whether it is in vitro fertilization or artificial insemination, oocytes are indispensable. When the IVF is completed, only when the egg cells have grown to a certain size, we will need to do a special drug treatment, which is also a very important step, called the night injection. So, how big should the egg be when giving the night injection? Can the egg still be produced after the night injection? Let's take a look together.

The egg will continue to grow after the night injection, but there is no need to worry. When arranging the time for the night injection and IVF egg retrieval, the doctor has taken into account various possible problems, but sometimes things go wrong. Some people will find that the eggs have been released or have been released during the IVF egg retrieval process. If released eggs are found, pelvic fluid will be collected to search for possible released eggs. If the egg is mature and not contaminated, it can be fertilized and can help achieve pregnancy, but this situation is relatively rare. If you experience uterine and ovarian pain or lower abdominal pain after the night injection, it is recommended that you do not do strenuous activities and wait quietly for the egg retrieval time for IVF. The egg retrieval rate will be higher because external force will increase the egg's support after the egg grows and may increase the chance of ovulation. Therefore, patients are generally advised to rest after the night injection and do not do strenuous activities.

During the IVF treatment process, when the egg develops to a certain stage, we need a special drug to promote the final perfection of the oocyte. It is the last and most important step in IVF ovulation induction - "night injection". This injection is human chorionic gonadotropin (HCG) or short-acting gonadotropin-releasing hormone inhibitor (GnRH-a). The injection time is usually arranged at night, so it is called the "night injection". Because the egg retrieval operation is carried out about 36 to 37 hours after the night injection.

The timing of the night injection is very critical. If the injection time is too early, the shape and function of the egg are not fully developed, there is not enough LH protein kinase on the egg granulosa cells, and it cannot respond appropriately to HCG. The cumulus nitric oxide synthase is insufficient and loose and tightly wrapped around the oocyte. The oocyte cannot fall off during air pressure aspiration during IVF egg retrieval, resulting in a low egg retrieval rate. Finally, it may also affect the perfection rate of the oocyte, and may have a negative impact on the fertilization rate and cleavage rate. If the injection time is too late, the oocytes may have been over-mature, the quality has decreased, or even have been expelled prematurely. Even if the oocytes are obtained, the best time for fertilization has passed.

The above is a detailed introduction to the relevant content about how big the eggs should be for night injections. In short, generally speaking, your doctor needs to combine your follicle size, estrogen level, risk of ovarian irritation syndrome and other factors to determine the time of night injection. Because everyone's conditions are different, such as the number of eggs and the level of female hormones. Therefore, the drugs used and the dosage are also different.