Normal values ​​of six follicular hormones

The follicular phase is a relatively important period. During this period, there are certain hormone tests. There are six items of hormones that should be checked. Generally speaking, during the follicular phase, women should focus on their bodies. These hormones have certain normal values, but many people do not know their specific normal values. So what are the normal values ​​of the six follicular hormones?

There is no complete and unified gynecological endocrine hormone measurement value in China. Moreover, due to the different sources of various reagents, measurement methods, data calculations, and units used, even for the same hormone sample, the results obtained by different laboratories are not exactly the same.

By measuring the levels of sex hormones, we can understand the female endocrine function and diagnose diseases related to endocrine disorders. The six commonly used sex hormones, namely follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), progesterone (P), testosterone (T), and prolactin (PRL), basically meet the needs of clinicians for screening of endocrine disorders and general understanding of physiological functions.

The six-item sex hormone test has many tests that can detect many diseases. Therefore, as a common examination item, the six-item sex hormone test is a commonly used examination method for patients with endocrine disorders. Through the six-item sex hormone test, it can be determined whether the patient has endocrine diseases, and then the treatment method can be determined according to the test results.

2. Estradiol (E2): Secreted by the ovarian follicles, its main function is to promote the transition of the endometrium into the proliferative phase and promote the development of female secondary sexual characteristics. The concentration of blood E2 is 48-521 pmol/L in the preovulatory period, 70-1835 pmol/L in the ovulatory period, and 272-793 pmol/L in the postovulatory period. Low values ​​are seen in ovarian dysfunction, premature ovarian failure, and Sheehan's syndrome.

3. Progesterone (P): Secreted by the corpus luteum of the ovary, its main function is to promote the transition of the endometrium from the proliferative phase to the secretory phase. The blood P concentration is 0-4.8 nmol/L before ovulation and 7.6-97.6 nmol/L in the late ovulation period. Low blood P values ​​in the late ovulation period are seen in luteal insufficiency, ovulatory dysfunctional uterine bleeding, etc.

5. Prolactin (PRL): It is secreted by the lactating trophoblast, one of the eosinophilic cells in the anterior pituitary gland. It is a simple protein hormone whose main function is to promote breast hyperplasia, milk production and milk discharge. During the non-lactation period, the normal value of blood PRL is 0.08-0.92nmol/L. A level higher than 1.0nmol/L is called hyperprolactinemia. Excessive prolactin can inhibit the secretion of FSH and LH, inhibit ovarian function, and inhibit ovulation.

6. Follicle-stimulating hormone (FSH): A glycoprotein hormone secreted by the alkaliphilic cells of the anterior pituitary gland. Its main function is to promote the development and maturation of ovarian follicles. The concentration of blood FSH is 1.5-10mIU/ml in the pre-ovulation period, 8-20mIU/ml in the ovulation period, and 2-10mIU/ml in the post-ovulation period. Generally, 5 to 40 mIU/ml is considered normal. Low FSH values ​​are seen during estrogen-progestin therapy, Sheehan's syndrome, etc. High FSH levels are seen in premature ovarian failure, ovarian insensitivity syndrome, primary amenorrhea, etc.