What happens if endometriosis causes no ovulation?

The uterus is the place where women give birth and nurture babies, so the uterus is also called the palace of the fetus. The physiological process by which the endometrium proliferates, thickens, sheds, and exfoliates as the menstrual cycle changes. However, endometriosis means that the endometrial tissue grows in tissues other than the endometrium, the most common of which is ectopic location in the ovaries. This will affect the ovulation process. Why does endometriosis affect ovulation?

There are many causes of infertility caused by endometriosis. Normal conception is an extremely delicate process. First, a mature egg is picked up by the fimbria of the fallopian tube after ovulation, and transported to and stays in the ampulla of the fallopian tube, where it meets the sperm and becomes a fertilized egg. It is then transported to the uterine cavity by the fallopian tube and implanted in the endometrium. Abnormalities in any link can lead to infertility.

First, patients with endometriosis often have abnormal ovarian function, and 17% to 27% of patients have ovulation disorders, which may be related to the increase of prostaglandins in the peritoneal fluid. When the follicle develops to maturity and is ready for ovulation, luteinization occurs, but the follicle is ultimately not released. Basal body temperature testing and ovulation test strip testing are the same as normal ovulation. This is one of the causes of infertility.

Secondly, the function of the fallopian tube to transport eggs decreases. Ectopic endometrium can grow in the ovaries or fallopian tubes, causing extensive adhesions around them and leading to obstruction, twisting, or blockage of the fallopian tubes. The fallopian tubes are not functioning properly and cannot transport sperm to the designated location to meet the egg.

Furthermore, the impact on fertilization: ectopic endometrium grows in the pelvic and abdominal cavity. In patients with endometriosis, especially those with dysmenorrhea, the microenvironment of the abdominal cavity changes, and a large number of cytokines exist, which harm sperm and fertilized eggs.

Next, the impact on implantation: Studies have found that the endometrium of patients with endometriosis is abnormal, and changes in the intrauterine environment will affect the implantation of the fertilized egg.

Finally, the spontaneous abortion rate in women with endometriosis is as high as 40%, while the spontaneous abortion rate in normal women is only 15%.

Endometriosis is quite dangerous. Not only will it disrupt women's menstruation, but it will also damage the function of the ovaries. It is very likely that ovulation will not occur, or the ovulation process is abnormal and cannot be implanted in the endometrium. Therefore, the chance of miscarriage is very high. People with endometriosis generally experience menstrual disorders, abdominal pain, and irregular vaginal bleeding, which require timely treatment.