What to do if a woman has high testosterone

Many women don’t know what testosterone is. Testosterone is a hormone in the female body. When the hormone is normal, it has many protective effects on women. However, if the testosterone is abnormal, and the female testosterone is high, then the harm is very great. High testosterone means that the female’s life has gradually become abnormal, and there are concerns that such a phenomenon will affect the female’s fertility. This phenomenon may also be due to excessive secretion of the adrenal cortex. So what should women do when their testosterone is high?

Excessively high testosterone levels have a certain impact on pregnancy, but most women can become pregnant naturally after treatment. What should girls do if their testosterone level is too high? Under normal circumstances, the testosterone level in women's serum is stable within a certain range. If it exceeds the normal value, it indicates the possibility of disease. During the follicular phase of a normal menstrual cycle, the average serum testosterone concentration is 0.43 ng/ml, with a maximum limit of 0.68 ng/ml. If it exceeds 0.7 ng/m1 (equal to 2.44 nmol/L), it is called hypertestosteronemia or hyperandrogenism.

The most common causes of elevated testosterone are polycystic ovary syndrome, accounting for about 34%, followed by hyperfunction of the adrenal cortex, accounting for about 29%; thirdly, it can be seen in hyperplasia of the follicles and adrenal cortex; in addition, hyperinsulinemia can stimulate the ovaries to secrete a large amount of androgen, resulting in hypertestosterone; about 28% are of unknown origin.

The ovaries, adrenal cortex, etc. can synthesize cholesterol from acetic acid, or absorb cholesterol from the blood as a matrix, synthesize steroid hormones, and secrete them into the blood circulation. The male hormones circulating in the blood mainly include dehydroepiandrosterone sulfate, dehydroepiandrosterone, androstenedione, testosterone and dihydrotestosterone. Hypertestosteronism is caused by excessive levels of these hormones, especially testosterone, in the blood.

The reasons for excessive androgen in serum are mostly due to excessive secretion of the ovaries or adrenal cortex; it may also be caused by abnormal peripheral conversion; it is an enzyme system disorder in the biosynthesis of steroid hormones, such as aromatase deficiency, androstenedione cannot be converted into estrone, and testosterone cannot be converted into estradiol, resulting in excessive accumulation of androstenedione, especially testosterone; 60% of testosterone is bound to β-globulin in the blood, called testosterone-estradiol binding globulin (TEBG), about 38% (mainly androstenedione) is bound to albumin, and free testosterone accounts for only 2%, but it is active. What should girls do if their testosterone level is too high? If the level of TEBG combined with estradiol increases and the level of combined testosterone decreases, the free testosterone in the blood will increase; hyperinsulinemia caused by insulin resistance can stimulate the ovaries to secrete a large amount of androgen.

When a woman has high testosterone levels, she should use the above methods to solve the problem in time. Otherwise, if testosterone continues to rise, the impact on fertility will become increasingly greater. Active treatment is the best way to prevent this consequence, but when the testosterone level is better, you must pay attention to science, do not believe in superstition, and do not go to unprofessional hospitals for treatment. This will only worsen your disease and cause symptoms such as ineffective treatment.