Severe intrauterine adhesions and successful IVF

There is a significant relationship between the severity of intrauterine adhesions and infertility. Although the success rate of IVF with intrauterine adhesions will be affected to a certain extent, it can be seen in clinical medicine that many such friends have successfully become pregnant. Therefore, uterine adhesions can lead to successful IVF pregnancy. As for the success rate, it mainly depends on the degree of adhesion, as well as the woman's physical condition, uterine and ovarian condition, egg condition, sperm condition... Although IVF is to take the sperm and egg cells of the couple out of the body and carry out IVF and IVF embryo formation in a laboratory environment, and then perform genetic screening before IVF transplantation, and then transplant healthy and high-quality IVF embryos into the pregnant mother's uterus to continue growth and development to achieve the purpose of eugenics, but the fertilized egg must implant and develop normally to have a chance to give birth to a baby successfully.

Intrauterine adhesions usually occur after spontaneous abortion or surgical abortion. Severe intrauterine adhesions will affect normal pregnancy, because intrauterine adhesions are related to pregnancy in about 91%. So how can you have a normal pregnancy when you encounter intrauterine adhesions? Because the severity of intrauterine adhesions is closely related to infertility, and it is sometimes difficult to predict the occurrence of infertility and miscarriage, for patients with intrauterine adhesions, this situation is very complicated. We will explain to you how to rely on the third generation of foreign test tube pregnancy for intrauterine adhesions!

Intrauterine adhesions are histologically manifested by the absence of normal uterine wall, uterine wall fibrosis, the glandular ducts are covered by non-metabolic columnar squamous epithelial cells, some stroma may also thicken or ossify, the glandular ducts become very scarce or nonspecific, most of the endometrial tissue lacks blood vessels and is scarred, and has no response to hormone stimulation. Many people may not understand this statement. In fact, to put it simply, the uterine wall is the "soil" for the sperm and egg to combine and settle. Once uterine adhesion occurs, the damaged uterine wall will affect the sperm and egg to "settle down" and "take root" in the uterine cavity, thus causing infertility.

So what are the effects on patients with intrauterine adhesions undergoing in vitro fertilization abroad? In fact, everyone knows that in vitro fertilization abroad is an artificial assisted reproductive technology. It is to take the sperm and egg cells of the couple out of the body and carry out in vitro fertilization and test tube embryo formation in a laboratory environment, and then carry out genetic screening before test tube transplantation, and then transplant healthy and high-quality test tube embryos into the pregnant mother's uterus to continue growth and development, so as to achieve the purpose of eugenics.

In this process, the IVF technology only replaces the function of the woman's fallopian tubes, and in the end the patient still needs to carry the baby for ten months. This is also the reason why in vitro fertilization has high requirements for the uterine environment.

Therefore, intrauterine adhesions will have adverse effects on pregnancy or in vitro fertilization abroad.

After adhesions occur in the uterine cavity, the uterine wall is damaged and cannot undergo regular changes under the influence of uterine and ovarian hormones, resulting in amenorrhea clinically. In addition, the adhesion of the uterine cavity blocks the safe passage of sperm to the fallopian tubes, so that the sperm and egg cannot combine to form sperm-egg fusion; even if sperm and egg fusion occurs, the adhesion of the uterine cavity also makes the sperm and egg fusion lose the place for embryo implantation, growth and development. Therefore, it often leads to infertility, difficult pregnancy, miscarriage, premature birth and other adverse effects on patients.

So, how do patients with intrauterine adhesions do IVF abroad?

In clinical medicine, many patients with intrauterine adhesions try to get pregnant through IVF abroad, and many of them are successful. So what is the reason?

In fact, for patients with intrauterine adhesions who are undergoing IVF abroad, different specific methods need to be adopted according to the situation, for example:

1. Cervical adhesions. If it does not affect in vitro fertilization (IVF) and IVF transplantation abroad, then IVF can be done without any corresponding treatment; 2. Uterine cavity adhesions. For such situations, it is generally recommended to perform hysteroscopy to separate the adhesions first, and then perform IVF based on the degree of postoperative intrauterine recovery. It is usually considered after 2-3 months of rest; 3. Connective tissue-like high-density adhesions. This situation generally requires hysteroscopy to separate the adhesions first, and then place an IUD in the uterine cavity after surgery. In this way, it will not affect in vitro ovulation treatment and IVF egg retrieval abroad, but the IUD needs to be removed before transplantation.

Therefore, different conditions of intrauterine adhesions have different solutions for in vitro fertilization abroad. As for how to do it, it is important to look at the patient's specific condition and combine it with the doctor's advice to solve it. Of course, this is not only for the purpose of promoting pregnancy through in vitro fertilization, but also for the purpose of increasing the success rate of in vitro fertilization abroad.

In addition, I would like to remind everyone that data show that the re-adhesion rate after hysteroscopic adhesion separation surgery for patients with moderate to severe intrauterine adhesions is as high as 62.5%, and the pregnancy success rate is only 22.5% to 3.3%. Moderate to severe intrauterine adhesions are prone to recurrence after treatment, and surgical treatment is often repeated. Therefore, such patients must be patient and not rush when undergoing treatment and promoting pregnancy.

Therefore, women with uterine adhesions do not need to worry, relax, and follow the doctor's plan for treatment to improve their uterine environment, which will be more conducive to IVF abroad!