What medicine should I take for simple uterine hyperplasia?

Endometrial hyperplasia is more common among women, most of which are simple hyperplasia. When a woman is diagnosed with simple hyperplasia of the uterine wall, she should be treated promptly. In addition to surgical treatment, she should also cooperate with some drugs to adjust and control, otherwise it may lead to poor treatment effect. So, what medicine should I take for simple uterine hyperplasia?

1. Estrogen, estrogen therapy, which is often called artificial cycle, usually starts on the 5th day of the next menstrual period, once a night, for a cycle of 20 days, and then takes the medicine for 7-10 days, and then takes medroxyprogesterone, appropriately every day, and continues for 3 cycles as a course of treatment.

2. Estrogen-progesterone synergistic treatment: For those with endometrial hyperplasia with thick endometrium and heavy menstrual flow, a small dose of emergency contraception can be taken on the fifth day of the menstrual cycle for three weeks. Withdrawal bleeding will occur after stopping the medication. One cycle is a course of treatment. Emergency contraception containing estrogen is used at the beginning, which can limit the effect of estrogen in promoting endometrial hyperplasia and make the excessively proliferated uterine wall shrink to normal thickness.

3. Estrogen second half cycle therapy: for bleeding due to endometrial hyperplasia after menopause, you can take progesterone orally for 10 days from the 16th to the 30th day of the menstrual cycle. If the amount of corpus luteum doubles, you can continue to take it for 5 days.

Treatment of simple uterine hyperplasia

For the treatment of intestinal metaplasia of the uterine wall, the diagnosis must be established first and the cause must be identified. If it is accompanied by polycystic ovary, ovarian tumors, or other endocrine and neurological disorders, targeted treatment should be given. At the same time, patients diagnosed with intestinal metaplasia of the uterine wall should start medication treatment immediately, using medication or surgical treatment. The choice of plan should be determined based on the patient's age, requirements for pregnancy, and health status. For those under 40 years old, the disease tendency is low and drug treatment can be considered first. Young people who are looking forward to having a baby should first use medication treatment, because after medication treatment, about 30% of patients are still likely to become pregnant and give birth to a full-term baby. For women before and after menopause, the potential development of the disease is higher than that of young people, so hysterectomy is often performed immediately.

1. The standard of medication treatment is

Standard medication, long-term examination, regular testing, and timely pregnancy promotion. Medication type: Clomiphene, a blood pressure-induced ovulation drug, is taken once a day from the 5th to the 9th day of the cycle. If necessary, the medication period can be extended by 2 to 3 days. Blood estrogen drugs: They vary according to the degree of endometrial atypia. Mild intestinal metaplasia can be treated with intramuscular injection of corpus luteum copper, starting on the 18th or 20th day of the cycle, and taken for a total of 5 to 7 days. Patients with mild to moderate and moderate to severe intestinal metaplasia should use medroxyprogesterone continuously for a course of 3 months. After each course of treatment, a curettage or removal of uterine wall tissue for histological examination is performed. Depending on the response to the drug, the patient can choose to stop treatment or consider adjusting the dosage of the drug as appropriate. An IUD can also be placed in the uterine cavity.

2. Surgery

Curettage is not only an important diagnostic method, but also one of the treatment methods. Because some diseases can be eliminated through curettage. Patients aged 40 years and above with intestinal metaplasia of the uterine wall who are not pregnant can undergo hysterectomy once diagnosed. However, for patients with hypertension, diabetes, obesity or the elderly who have poor tolerance to surgery, drug treatment can be considered first under strict follow-up testing. Young patients who have failed to respond to medication, whose endometrial hyperplasia continues or worsens or is suspected to have developed into cancer, or whose vaginal bleeding cannot be controlled by curettage and medication, and who relapse after childbirth, can all consider surgical hysterectomy.