Is low-grade squamous intraepithelial lesion (LSIL) serious?

In fact, the female uterus is a relatively fragile entity, so it is very necessary to go to the hospital regularly for uterine examinations, because this can promptly detect whether there are any uterine disease problems. Among them, cervical biopsy is an important examination item. Through this examination, whether there is the possibility of cancer around the cervix can be detected. So if low-grade squamous intraepithelial lesion (LSIL) is detected, is it serious?

1. Low-grade squamous epithelial lesions refer to precancerous lesions. This type of precancerous lesion is not serious and can be treated actively in the clinical setting. For example, do not have sex for 3-7 days after the menstruation stops, do routine tests of leucorrhea, blood routine, coagulation time, and do an electrocardiogram to understand whether the pelvic condition is normal. Then, laser treatment, microwave treatment, or cryotherapy can be performed. The main purpose is to cause necrosis and shedding of the cervical epithelium with low-grade lesions, and to grow new tissue to achieve the treatment goal. Corresponding examinations should be performed 3 months, 6 months, and 1 year after treatment. If there are no abnormalities, cervical cancer screening should be done once a year.

2. Low-grade squamous epithelial lesions are not serious clinically. Due to HPV infection, they can also cause high-grade precancerous lesions of the cervical epithelium. Therefore, for low-grade squamous epithelial lesions, clinically, appropriate intervention is needed, such as microwave treatment, laser treatment or cryotherapy of the cervix, which mainly causes the diseased tissue to necrotize and fall off, and then new normal tissue grows. Regular check-ups are necessary after surgery, mainly to understand whether there are still lesions in the cervical epithelium or whether there is still high-risk HPV infection. If there is a high-risk HPV infection, it should be given enough attention clinically, because persistent infection with high-risk HPV will lead to precancerous lesions of the cervix or even cervical cancer. If local lesions of the cervix are found clinically, timely treatment should be given to prevent further development of the disease.

3. Clinically, if a cervical biopsy indicates low-grade squamous intraepithelial lesion, this result indicates a first-grade cervical precancerous lesion. Different treatment options are available depending on the patient's age and whether or not they desire to have children. If the patient is young and has fertility needs, conservative drug treatment or laser treatment is recommended for low-grade squamous intraepithelial lesions. Because if the cervical conization is performed directly, it may cause the cervical canal to shorten, which may lead to threatened premature birth, cervical insufficiency and other conditions in future pregnancies. Under normal circumstances, through conservative drug treatment or laser treatment and regular enhancement of immunity, the conversion rate of low-grade squamous intraepithelial lesions to negative is as high as 70%. A very small number of patients will develop stage II or III cervical precancerous lesions. If disease progression occurs, cervical conization is recommended. However, if the patient is older and has no fertility needs, the negative conversion rate is relatively low. It is recommended to perform cervical conization directly. Postoperative cervical reexamination is generally normal.