What are the hemostatic drugs for gynecology?

Women often experience heavy bleeding during childbirth or abortion. What are the gynecological hemostatic drugs? There are many drugs used for gynecological hemostasis in both traditional Chinese medicine and Western medicine. The Chinese herbal medicines commonly used to stop bleeding for women in traditional Chinese medicine include Platycodon grandiflorum, Bletilla striata, Artemisia argyi, Sophora japonica, and Agrimoniae scabra. The drugs used to stop bleeding for women in Western medicine include posterior pituitary hormone, tranexamic acid, thrombin, etc. Let's learn about them in detail.

1. Principle of hemostasis

The principles include coagulation and vasoconstriction, as well as physical and physiological principles.

The principles of Platycladus orientalis leaves and Imperata cylindrica roots are physiological. Some bleeding is caused by blood heat, and they have the effect of cooling the blood, so there is a balance to achieve the hemostatic effect; the principle of action of Panax notoginseng is related to the liver and should also be physiological.

The principle of Bletilla striata to stop bleeding should be physical, which is related to the colloidal components it contains. It can form a protective film on the wound surface and agglutinate with red blood cells to form a thrombus to achieve the hemostatic effect.

The working principle of Sophora japonica flower is to reduce the permeability of blood vessels.

The working principle of pollen, crane herb, charcoal, wormwood, dandelion and palm is blood coagulation.

2. Commonly used hemostatic drugs in medicine

1. Hemostatic drugs acting on blood vessels

Posterior pituitary hormone: rupture and bleeding of esophageal varicose veins, ulcers, acute gastric mucosal injury, and cardiac mucosal tear.

Norepinephrine: acts on the arterioles and capillaries in the gastrointestinal mucosa, causing them to contract strongly.

Somatostatin: upper gastrointestinal bleeding, pancreatitis, food rupture.

Carbaclot/Carbosalate: nosebleed, uterine bleeding, cerebral hemorrhage, etc.

Ethylphenolsulfonamide: prevents bleeding before and after surgery, gastrointestinal bleeding, etc.

2. Antifibrinolytic drugs

Tranexamic acid: Bleeding caused by hyperfibrinolysis and severe bleeding caused by excessive thrombolysis.

3. Thrombin

Thrombin: Local hemostasis of small blood vessel or capillary bleeding, traumatic bleeding, oral use for upper gastrointestinal bleeding.

Prothrombin complex: bleeding caused by coagulation factor deficiency, sodium diphacin poisoning.

Snake Venom Hemocoagulase: Various medical conditions where it is necessary to reduce or stop bleeding.

4. Drugs that promote the activation of coagulation factors

Vitamin K1: neonatal hemorrhagic disease, biliary colic, etc.

Some Chinese herbal medicines also have good hemostatic effects, such as Yunnan Baiyao, Panax notoginseng, Zhixueling, Herba Agrimoniae, Bletilla striata, Lithospermum officinale, Rubia cordifolia and Imperata root.

3. Gynecological hemostatic drugs

Commonly used oral hemostatic drugs include Yunnan Baiyao, Gongxuening Capsules, Vitamin K, Duanxueliu Capsules (Tablets), Anluoxue, Hemostatic Aromatic Acid, Hemostatic Min, Fuxuean Tablets and Fuxuekang Granules.