Is pyelonephritis serious in women?

The bladder is also a very important urinary organ in the body. The main function of the bladder is to store urine. However, if you hold your urine for a long time, it can easily cause cystitis. If cystitis is not treated promptly, it is likely to cause pyelonephritis, which will cause serious damage to the patient's kidneys. So how serious is the problem of pyelonephritis in women?

Causes of pyelonephritis in women

1. If cystitis is not treated promptly or adequately, about 30% to 50% of cases may develop into pyelonephritis.

2. Renal parenchymal lesions, such as glomerulonephritis, renal cysts, renal tumors and chronic tubulointerstitial diseases. It can reduce the local antibacterial ability of the kidney and make it more likely to develop pyelonephritis.

3. Because female urethra is short, bacteria can easily invade and there are more chances of infection, so the incidence rate is 8 to 10 times higher than that of males.

4. Systemic factors, such as hypertension, long-term hypokalemia, heart failure and many chronic wasting diseases are prone to complications of this disease.

5. The presence of E. coli in the female urethra is often an important cause of this disease.

6. Pregnant women have increased estrogen secretion, decreased ureteral tension, and weakened peristalsis, which leads to urinary tract obstruction and a higher incidence of urine reflux. Therefore, most urinary tract infections during pregnancy are pyelonephritis. It is mostly caused by ascending infection from cystitis, especially bladder-ureteral reflux, which is an important cause of ascending infection.

The dangers of pyelonephritis in women

1. Patients with pyelonephritis will have some systemic symptoms, the main symptoms are: high fever chills, frequent urination, urgency, pain, turbid urine, accompanied by low back pain, etc. If not treated in time, the disease may lead to hypertension, uremia and other symptoms due to decreased renal function in the later stages.

2. The harm of chronic pyelonephritis is also very great. Most serious complications of urinary tract infections are related to pyelonephritis in children. Although pyelonephritis recurs, adult patients with normal kidney and urinary system development rarely develop renal scarring or loss of function. However, adult patients with kidney infection complicated by diabetes, urinary tract stones, and urinary tract obstruction are at risk of progressive renal damage and loss of function.

3. Repeated attacks of pyelonephritis can also cause multiple scars, resulting in intrarenal obstruction and deformation of the renal pelvis and calyces, and evolve into chronic pyelonephritis. The bacterial antigens remaining in the lesions during the acute phase can stimulate the body to produce antibodies, causing an immune response, causing the inflammation to persist and turn into a chronic disease.

4. Concurrent infectious stones: The main component of the stones is magnesium ammonium phosphate. This is because the urease contained in Proteus and other bacteria can decompose urea in urine, making the urea alkaline. The solubility of phosphate in alkaline urine is significantly reduced, and it is easy to precipitate and form magnesium ammonium phosphate and apatite stones.