Symptoms of Group B Streptococcus in Pregnant Women

Pregnant women should take good care of their bodies during pregnancy and try not to have any problems with their bodies, otherwise it will affect the fetus in their belly. If a group B streptococcal infection occurs, many pregnant women will be very worried about their bodies, fearing that it will cause a great impact on the fetus in their belly. In fact, at this time, you must be cautious when using drug treatment.

Severe streptococcal infection mainly refers to bacteremia, STSS, necrotizing fasciitis, myositis, etc. caused by streptococcal infection, while meningitis caused by streptococci has relatively mild symptoms and a better prognosis.

The main clinical manifestations of STSS are: sudden high fever, petechiae and ecchymoses in distal parts, gastrointestinal symptoms and shock in the early stage, rapid transition to multiple organ failure, especially kidney failure, the heart and liver are also easily affected, and respiratory distress syndrome is prone to occur. The mortality rate is high. Such cases have been reported both at home and abroad.

Necrotizing fasciitis and myositis refer to a terrible disease caused by streptococci (mainly group A invasive streptococci) in which the skin itself is not necessarily damaged, but the fascia, muscle, and fat tissue deep in the subcutaneous tissue rapidly necrotize. Therefore, the bacteria are also called "flesh-eating bacteria."

(I) Clinical manifestations: Patients with the above clinical manifestations and diagnosed with STSS have at least two or more organ failures accompanied by shock; patients diagnosed with necrotizing fasciitis and myositis must meet the clinical manifestation characteristics of necrosis in the deep subcutaneous tissue. (ii) Streptococci are isolated from the patient's sterile sites (such as blood, cerebrospinal fluid, etc.) or lesion sites; or there is a history of direct contact with sick or dead animals infected with Streptococci, and there is skin damage at the contact site.

treat

In the early stages of the disease, large amounts of penicillin combined with other broad-spectrum antibiotics can be used for treatment. In the late stages of the disease, any antibiotics should be used with caution, especially for patients with renal failure. Antibiotics should not be used. Treatment should mainly be symptomatic and supportive. Dialysis can be performed when necessary, and attention should be paid to the patient's acid, alkali, and electrolyte balance.

Streptococci are round cocci that occur singly, in pairs, or in short chains of several, or in long, beaded chains. They generally have no flagella, do not move (except for some strains of group D), and do not form spores. Some strains can form biofilms in diseased materials or in culture media containing serum. Gram staining is generally positive, while older cultures are mostly negative.

Pathogenic streptococci grow well on culture media containing serum and fresh blood. Fresh blood agar culture is generally used to observe hemolysis. This bacterium is facultative anaerobic, but it is obviously hemolytic in the absence of oxygen. The optimum culture temperature is 37°C. The colonies are small, 1-2 mm in diameter, transparent, shiny, smooth, round, with neat edges. Pathogenic streptococci mostly belong to the hemolytic streptococci (β group).