Effects of Coenzyme Q10 on Follicles

During the preparation for pregnancy before IVF, I often heard about a health product called coenzyme Q10. I heard that many IVF organizations strongly recommend its use to improve the quality of sperm and eggs, especially for women over 35 years old. It is best to start taking it half a year or more in advance to help improve the quality of ovaries and eggs and increase the success rate of IVF. What is Coenzyme Q10 actually for?

What is Coenzyme Q10

Coenzyme Q10 (Coenzyme Q10, CoQ10), also known as ubiquinone, is a fat-soluble quinone compound that participates in the production of cellular ATP in cells. It is an important cellular antioxidant, and its tissue concentration is 5-10 times that of other important lipid antioxidants such as VE.

During the preparation for pregnancy before IVF, I often heard about a health product called coenzyme Q10. I heard that many IVF organizations strongly recommend its use to improve the quality of sperm and eggs, especially for women over 35 years old. It is best to start taking it half a year or more in advance to help improve the quality of ovaries and eggs and increase the success rate of IVF. What is Coenzyme Q10 actually for?

What is Coenzyme Q10

Coenzyme Q10 (Coenzyme Q10, CoQ10), also known as ubiquinone, is a fat-soluble quinone compound that participates in the production of cellular ATP in cells. It is an important cellular antioxidant, and its tissue concentration is 5-10 times that of other important lipid antioxidants such as VE.

In order to understand this definition, we first need to understand the relationship between oocytes and membrane proteins.

The egg contains granulosa cells, egg fluid, and oocytes. The energy required for oocyte metabolism is completely provided by membrane proteins. The oocyte contains more membrane proteins and membrane protein DNA than any other cells. During uterine development, membrane protein DNA increases from 6000 copies to 20,000, accounting for 50% of the total DNA of the oocyte.

As women and oocytes age, oxidative phosphorylation of membrane proteins in oocytes decreases, and abnormalities are found in the process of oocyte maturation, especially in meiosis and sex chromosome separation. The result is often an increased incidence of aneuploidy, especially triploidy, in the descendants of older women.

Effect of Coenzyme Q10 on the Complex Enzymatic Reaction of the Respiratory Chain of Oocyte Membrane Proteins in IVF Patients

The hydrolysis of the membrane protein respiratory chain is: ATP is produced through the redox reaction process to provide energy for the cell

This provides higher membrane protein production efficiency for oocyte improvement and embryo development, while reducing chromosome separation disorders and improving the ability of test tube embryo implantation in older patients.

Clinical trials show that coenzyme Q10 can improve the treatment effect of older infertility patients

The composition of Coenzyme Q10 in common food ingredients

Although there are many foods in daily life that contain coenzyme Q10, their ingredients cannot supplement sufficient coenzyme Q10. You need to consume 1 pound of tuna, 2 pounds of beef or 3 pounds of peanuts every day to provide about 30mg of coenzyme Q10. Therefore, a better way is to extract coenzyme Q10, so that it can be supplemented better.

Coenzyme Q10 application range

Athletes, people working with brains, people pursuing beauty, people with poor immunity, smokers and drinkers, people who get easily fatigued, and elderly people preparing for pregnancy will benefit greatly from moderate supplementation of coenzyme Q10.

Supplementing coenzyme Q10 can help improve the condition of patients with heart disease, chronic fatigue syndrome, periodontitis, gastrointestinal ulcers, nerve damage, senile degenerative diseases, Alzheimer's disease, diabetes, etc.

If the bleeding gums are more serious, in addition to supplementing vitamin C, you should also take more coenzyme Q10.

Coenzyme Q10 intake time and method

Coenzyme Q10 can be taken orally or applied topically. There is no fixed time for taking it, and it can be taken at any time of the day. Generally speaking, the recommended daily dosage should not exceed 30-60 mg for oral administration. If there are special needs, it can be increased to 100-300 mg per day.

It is worth mentioning that although the actual effect of coenzyme Q10 is good and no side effects of coenzyme Q10 have been found at this stage, it is not recommended to take high concentrations of coenzyme Q10 for a long time, as it will cause defects in the ability to produce coenzyme Q10.

The above consumption method and dosage are for reference only. The actual dosage should be based on the product manual or doctor's instructions. The supplementation of coenzyme Q10 has no effect on the supplementation of other health products, but the combination and dosage of combined drugs in the auxiliary treatment of some diseases should be based on the patient's own condition and follow the doctor's specific instructions.