​From which day of menstruation should ovulation be stimulated?

If a woman's ovaries are not fully developed, it will affect the normal discharge of eggs, and thus affect a woman's normal fertility. At this time, if a woman wants to get pregnant, she needs external force to promote the release of eggs. This method is called ovulation induction. However, if you want to promote ovulation, you also have to consider the woman's physical condition. So generally speaking, if we want to promote ovulation, from which day of menstruation should we start?

If women have abnormal ovulation due to polycystic ovary syndrome or other reasons, such as premature ovarian failure or ovarian dysfunction, and they want to get pregnant, they can consider using drugs to induce ovulation. Generally speaking, for women with normal menstruation, drugs for ovulation induction can be taken orally starting from the fifth day of menstruation, and a transvaginal ultrasound can be performed five days later to monitor the development of follicles. When you see that the follicle is about to be released, start planning sexual intercourse to prepare for pregnancy. For women who do not have menstruation, they can start ovulation induction anytime and anywhere, also by taking it orally for five consecutive days, and then monitoring with vaginal ultrasound. If the enlarged follicles are not completely discharged, you can also consider giving them a urine-stimulating injection to promote the discharge and rupture of the follicles.

How many times can you induce ovulation to get pregnant?

Ovulation-inducing drugs are mainly used to treat those who have no ovulation due to dysfunction of the hypothalamus-pituitary-ovarian axis. Taking drugs can induce ovulation. There are many kinds of ovulation-inducing drugs in clinical practice, and the methods and dosages of medication are completely different for different conditions. Generally, ovulation-inducing drugs are taken starting on the fifth day of menstruation. Female friends must follow the doctor's instructions and never take them on their own to avoid side effects of the drugs.

The effects of various ovulation-stimulating drugs are as follows:

1. Clomiphene: Starting from the 5th day of menstruation, take clomiphene 50-150 mg/day orally for 5 consecutive days. You may ovulate 5-11 days after stopping the medication. If the estrogen level is low, you can first use a small dose of estrogen, diethylstilbestrol 0.125-0.25 mg/day, for 20 consecutive days and 1-3 cycles to increase the sensitivity of the hypothalamus-pituitary-ovarian system, and then use clomiphene to induce ovulation to improve the efficacy. If the cervical mucus is small and thick, add diethylstilbestrol 0.125-0.25 mg/day after taking clomiphene for 7 consecutive days.

2. Artificial cycle of estrogen and progesterone: For those with general menstrual disorders but a certain level of estrogen, estrogen and progesterone can be used sequentially for artificial cycle treatment for 3 months. Ovulation may occur after stopping the medication.

3. Human chorionic gonadotropin (hCG): hCG has the effect of luteinizing hormone and can promote ovulation when administered when the follicles are nearly mature.

4. Luteinizing hormone-releasing hormone (LH-RH): Suitable for anovulators with insufficient secretion of the hypothalamus. Use micropump pulse intravenous injection, with pulse intervals of 90-120 minutes, small doses of 1-5 μg/pulse, large doses of 10-20 μg/pulse, for 17-20 days, or starting from the 5th day of the menstrual cycle, intramuscular injection of 50 μg daily for 7-10 consecutive days.

5. Bromocriptine: Suitable for people with anovulation and hyperprolactinemia.