There are several types of breast cancer

In clinical medicine, doctors have encountered many breast cancer patients asking questions such as the type of disease, serious consequences and whether they will die. In fact, the tissue shape of breast cancer is very complex and there are many types. There may even be two or more varieties in the same slice. Among them, invasive breast cancer is the main type of breast cancer. Let’s take a look at the types of breast cancer with the editor below!

Type 1 of breast cancer: non-invasive cancer

It is the early stage of breast cancer. When the cancer tumor is confined to the mammary gland tube or alveolus and no extension of its basement membrane is seen, it is also called non-invasive cancer.

1. Cancer in the hose

The tumor cells were confined to the tube without elevating the thick basement membrane. Mostly produced in small hoses, large hoses are rare, and are generally distributed in multiple centers.

2Lobular carcinoma in situ

Cancer that arises in the squamous cells of the lobular tubes and peripheral nerve tubes is common in premenopausal women, and the age of onset is 5-10 years earlier than that of general breast cancer. The lobules were enlarged, the number of ducts and alveoli increased, and they became significantly wider, filled with apolar tumor cells. Lobular carcinoma in situ is more lagging and has a good prognosis.

Type 2 of breast cancer: Early invasive cancer

1 Early invasion of lobular carcinoma

The cancerous tissue breaks through the thick basement membrane and begins to infiltrate into the interstitial space of the lobules, but is still confined to the lobule area.

2. Early invasion of ductal carcinoma

The tumor cells of intraepithelial cancer break through the thick basement membrane and begin to sprout and invade into the interstitial space.

Breast cancer type 3: invasive idiotype carcinoma

1. Papillary carcinoma

Originated from the squamous epithelial cells of the large milk ducts, the carcinoma is essentially dominated by papillary structures with or without fibrous vascularization, and can be non-invasive and invasive papillary carcinoma. Its invasion usually occurs at the base of the papillary hyperplasia.

2 Medullary carcinoma with many reticulocyte infiltration

Necrosis and bleeding often occur in cross-section, and microscopy shows that there are many reticulocytes and plasma cells infiltrating in the stroma of large areas of cancer cells. It is more obvious in the area near the cancer and is generally considered to be the body's defense against the tumor.

3. Tubular carcinoma

It originates from tubular or small tubular squamous epithelial cells and is a type with a lower degree of malignancy and a good prognosis.

4Adenoid cystic carcinoma

Flakes or small stains of varying sizes and shapes are produced by somatic cells in the substrate, containing annular cavities of varying numbers but relatively uniform sizes. Myosquamous epithelial cells can be seen near the luminal surface and somatic cell sheets.

5. Hidradenoma

The tumor cells have rich, eosinophilic cytoplasm, sometimes with apical bulges, and slightly to moderately dysmorphic nuclei, forming glandular, alveolar or small papillary structures.

6. Mucinous Adenocarcinoma Level Questions

It occurs on the basis of mucous metaplasia of mammary epithelial cells and is common in women near menopause or after menopause, especially in women over 60 years old. In cancer essence, epithelial cell mucus accounts for more than half of the composition. Most of the mucus is outside the somatic cells, forming mucus lakes; a small amount is inside the somatic cells, forming signet ring-shaped somatic cells.

7Squamous cell carcinoma

Mammary gland epithelial cells derived from squamous metaplasia. The carcinoma was essentially a typical squamous cell carcinoma, in which intercellular bridges and keratinization were visible. If other types of cancer produce some squamous metaplasia, they are not included in this list.

8Paget's disease of the nipple

Also known as eczematous carcinoma of the nipple, this disease was first described by Paget (1874). After many years of scientific research, it is now believed that the tumor cells under the microscope are large in size, with rich and lightly stained cytoplasm, often vacuolated, large nuclei, significantly irregular, and a few nuclear division images.

Breast cancer type 4: Invasive non-idiotypic carcinoma

1Invasive lobular carcinoma

Lobular carcinomas have marked extralobular invasion, including small cell invasive carcinomas.

2Invasive ductal carcinoma

Ductal carcinoma significantly invades the interstitial space, but the invasion portion does not exceed half of the carcinoma parenchyma. If it exceeds half, it is named after the key shape of invasive cancer.

3. Sclerosing cancer

The tumor cells are arranged in thin bundles or scattered, rarely forming glandular structures, and the fibrous interstitial components account for more than two-thirds and are high-density.

4 Medullary carcinoma

Cancer nests are in the form of masses or small clusters, and may have glandular structures. The cancerous tissue accounts for more than two-thirds of the tissue, and there may be a small number of reticulocytes and plasma cells in the interstitial space.

5Simple cancer

It is close to between scirrhous cancer and medullary cancer, that is, the proportion of cancer essence and fibrous components is similar. The tumor cells mainly form irregular solid bundles or small stains, and may also have glandular structures.

6Adenocarcinoma

The tumor cells are of uniform size, with rich and colorful cytoplasm, metabolism, darkly stained nuclei, frequent mitotic figures, glandular arrangement, multiple layers, disordered optical rotation, lack of basement membrane, and infiltrative growth in the interstitial space. The tumor cells may also be arranged in cords or flakes, with glandular arrangement accounting for more than half.