Genital ejaculation is a disease that is mainly transmitted through sexual intercourse, and the main site of infection is the reproductive organs. People with chaotic sexual lives are generally very susceptible to infection, and if not treated in time, it may develop into cancer. Genital ejaculation usually occurs in women in their 20s. Because it affects a relatively private part of the body, many women fail to seek medical treatment in time, thus missing the best time for treatment. Below I will tell you what the symptoms of condyloma aureum are so that you can understand them. 1. What causes genital warts?HPV reaches the basal cells through the skin and mucous membranes damaged by sexual intercourse. The outcomes vary greatly due to the different HPV types, existence states, and immune status of the body. If infected with low-risk HPV, after the virus enters the host cells, its DNA is free outside the host chromosomes. HPV sheds its capsid in the basal cells, replicates its DNA in differentiated cells, synthesizes capsid proteins and packages the viral genome in granular cells, and complete virions appear in the stratum corneum cells. When the stratum corneum cells die and fall off, the virions are released and then infect the surrounding normal cells. The massive replication of the virus body stimulates the proliferation of epithelial cells, resulting in epidermal hyperplasia and thickening under the microscope, and the clinical manifestations are genital warts. If infected with high-risk HPV, its DNA is integrated into the host cell chromosomes and cannot produce complete virions. HPV E6 and E7 conversion genes are expressed, leading to the occurrence of intraepithelial neoplasia and invasive cancer. The symptoms of genital warts are often not obvious in cases of integrated infection.
The incubation period of genital warts is 3 weeks to 8 months, with an average of 3 months. It is more common in young women aged 20-29. The clinical symptoms are often not obvious, and most patients seek medical treatment for vulvar growths. Some patients experience vulvar itching, burning pain, or bleeding after sexual intercourse. The lesions are common in areas that are easily injured during sexual intercourse, such as near the navicular fossa, labia majora and minora, around the anus, vaginal vestibule, and urethral opening. The vagina and cervix may also be affected. 50%-70% of vulvar warts are accompanied by vaginal and cervical warts. Genital warts initially present as single or multiple small pink papules with sharp tips and nipple-like protrusions. As the disease progresses, the lesions gradually increase in size and number, and may appear cauliflower-shaped, cockscomb-shaped, or lumpy, with an uneven, peak-shaped surface. The warts are often white, pink, or dirty gray, soft, and brittle, and the surface may be ulcerated or infected. In a small number of patients with reduced immunity, warts may proliferate excessively and develop giant condyloma acuminatum.After the occurrence of genital warts, due to the interaction between HPV and the body's immune factors, the lesions in 10%-30% of patients may regress naturally, while the lesions in some patients may persist and further develop in some patients. Cervical lesions are mostly subclinical HPV infection, and no obvious lesions can be seen clinically, so they need the help of colposcopy and acetic acid test to assist in detection. |
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