What causes follicular atrophy?

If the follicles atrophy, there will be no normal eggs and women will not be able to conceive normally. Therefore, we should pay attention to understanding some of the causes of follicle atrophy and choose scientific treatment methods to effectively help induce ovulation.

1. Introduction

It refers to a group of syndromes in which the menstrual cycle is regular and ovulation is assumed to occur, but the follicle does not rupture in the middle of the menstrual cycle and ovulation does not occur. It is one of the important causes of infertility. Patients are often clinically diagnosed with unexplained infertility, corpus luteum deficiency, endometriosis or pelvic inflammatory disease. The possibility of this disease should also be considered in patients with ovulatory dysfunction who cannot become pregnant even after inducing "successful ovulation". In addition to the manifestations of the above diseases, patients may have no other symptoms. During examination, it can be found that they have regular menstrual cycles and the basal body temperature is biphasic; premenstrual diagnostic curettage and endometrium show secretory changes; after the basal body temperature rises, blood estrogen and progesterone may be within the normal range. This requires symptomatic treatment or combined surgical treatment based on the specific situation of the reproductive axis in order to have hope of having a child.

2. Reasons

The menstrual cycle is generally 32 days, and the 13th day should not be the time of ovulation. Generally, the follicle will rupture when it grows to about 1.8-2.5. If the follicle does not rupture but atrophies, it is a manifestation of luteinized follicle, and an endocrine examination is needed to determine the cause. Because there are many endocrine factors that cause follicular atrophy. The main problem is that estrogen levels cannot be raised, and endometrial thickening also indicates problems with hormone levels. If the follicles are indeed unable to be discharged and have atrophied, an endocrine examination should be done to find the cause, and then treatment should be given according to the cause to achieve the best results.

Treatment

1. General treatment: For young patients who do not have an urgent desire to have children, conservative treatment should be tried first, such as taking oral Chinese medicine to promote blood circulation and remove blood stasis.

2. Induce ovulation treatment:

3. Assisted reproductive technology includes artificial insemination, in vitro fertilization-embryo transfer and its derivative technologies.

How to distinguish ovulation and follicular atrophy on B-ultrasound? Ultrasound monitoring of ovulation usually begins on the 10th day of the menstrual cycle to observe changes in the diameter of the follicles. The diameter of the follicles increases by an average of about 3mm per day in the 4 days before ovulation. The follicles mature to about 17 to 25mm before ovulation and disappear after ovulation. Continuous monitoring shows that the follicles continue to grow before ovulation. When the largest follicle disappears, ovulation is indicated. The self-test rate of ovulation test strips is about 75%. If your menstrual cycle is regular, ovulation usually occurs about 14 days before the next menstrual period, but the exact day of ovulation cannot be predicted.