What are the drug contraindications in late pregnancy?

Women in the late stages of pregnancy should pay special attention to their physical condition, especially the taboos during pregnancy. There are also many drug contraindications in late pregnancy. Women must follow their doctor's orders when taking medication during pregnancy and avoid taking medication at will to avoid teratogenic factors.

1. Antibiotics.

Such as tetracycline, oxytetracycline, streptomycin, gentamicin, neomycin, etc. Tetracycline and oxytetracycline can cause fetal short limb deformity, fontanelle bulge, and congenital cataracts. Taking them in the late pregnancy can cause dental enamel hypoplasia in childhood. Streptomycin and gentamicin can damage the eighth cranial nerve of the fetus, leading to congenital deafness and kidney function. Neomycin can cause abnormal bone development, paradoxicals, renal and pulmonary arteriolar stenosis, congenital cataracts, and intellectual disability in the fetus.

2. Antimalarial drugs.

Such as quinine, chloroquine and pyrimethamine, can cause multiple malformations in the fetus. Such as deafness, limb loss, hydrocephalus, etc.

3. Drugs for treating diabetes.

Such as chlorthiopropamide, damikon, and glycosides, which can cause limb deformities, cleft lip, stillbirth, etc.

4. Barbiturates and other sedative-hypnotic drugs.

Such as phenytoin sodium, primidone, and tranquilizer, which can cause limb, facial, and brain malformations.

5. Anti-cancer drugs.

Such as dactinomycin, cyclophosphamide, 5-fluorouracil, thiotepa, etc., can cause anencephaly, hydrocephalus, cleft lip, cleft lip, kidney and ureteral defects, limb and eye deformities, etc.

6. Hormone drugs.

Such as ethinyl estradiol, progesterone, androgens, and cortisone. Oral contraceptives can cause malformations of the fetal reproductive organs. Such as masculinization of female fetuses, hypertrophy of the clitoris, fusion of the labia majora, and inferior urethra in male fetuses .

7. Anticoagulant drugs.

Drugs such as heparin, coumarin, aspirin, salicylic acid, etc. can also cause teratogenesis and induce hemorrhagic diseases. In short, care should be taken to avoid drug abuse during pregnancy. However, if there is an emergency situation that endangers the life of the pregnant woman and medication is necessary, the priority should be to save the life of the pregnant woman. Once the emergency situation is over, the dosage should be reduced or the medication should be stopped quickly. The idea that refusing to take medicine will affect the fetus is also wrong. If the life of the pregnant woman is in danger, how can the fetus be safe? Therefore, when it comes to the issue of medication for pregnant women, we should distinguish the primary and secondary contradictions and take them into comprehensive consideration.