Do you know what causes uterine tumors?

Uterine tumors are very common in middle-aged women, and the causes of uterine tumors are related to many factors. For example, age, mood, stress, hormone levels, genetics, etc. Currently, there is no clear clinical definition of the cause of uterine tumors.

1. General factors:

1. Age: Uterine fibroids mostly occur in women of childbearing age, more common in women aged 30-50. It is rare for adolescent women to have uterine fibroids. Uterine fibroids atrophy or disappear after menopause.

2. Obesity: Obesity can cause metabolic disorders, leading to lack of cyclical regulation of progesterone, causing abnormal menstrual cycles, affecting ovulation, and increasing the risk of uterine fibroids.

3. History of pregnancy and miscarriage: Women with a history of pregnancy and childbirth are more likely to develop uterine fibroids than women without a history of pregnancy and childbirth, and the age of onset is earlier, mainly because menstruation can increase the amount of progesterone in women's bodies.

4. Smoking and drinking: Smoking and drinking can easily induce uterine fibroids. Studies have shown that women who smoke a pack of cigarettes a day are six times more likely to develop uterine fibroids than non-smoking women.

2. Hormone levels:

1. High estrogen: Biochemical tests have confirmed that the conversion of estradiol to estrone in fibroids is significantly lower than that in normal muscle tissue, and the concentration of estrogen receptors in fibroids is significantly higher than that in surrounding muscle tissue. Therefore, it is believed that the high sensitivity of local fibroid tissue to estrogen is one of the important factors in the occurrence of fibroids.

2. High progesterone. Progesterone can promote mitosis of fibroids and stimulate their growth. If a woman has a high level of progesterone in her body, it is easy to induce uterine fibroids.

3. Genetic factors:

Cytogenetics show that 25%-50% of uterine fibroids have cytogenetic abnormalities, such as chromosome segment position exchange, chromosome long arm rearrangement or partial deletion, etc. Uterine fibroids are formed by the proliferation of monoclonal smooth muscle cells, while multiple uterine fibroids are formed by different clones of cells.