What are the symptoms of invasive hydatidiform mole?

For patients with invasive hydatidiform mole, they must be careful to avoid too much physical labor after getting the disease. They can only engage in some light activities, such as walking or jogging, and do some housework within their ability. Don't work too hard, and ensure good sleep quality. Hydatidiform mole is very harmful to the body. Here are some symptoms of invasive hydatidiform mole.

Invasive hydatidiform mole refers to hydatidiform mole tissue invading the myometrium of the uterus or with distant metastasis, also known as malignant hydatidiform mole or destructive chorioma. This tumor can penetrate the uterus, causing intra-abdominal bleeding, invade the broad ligament and cause hematoma, and can also metastasize to organs such as the vagina, lungs, and brain, and even cause death. Microscopically, the degree of trophoblastic cell proliferation and atypia are more significant than those in benign hydatidiform mole. Hemorrhagic necrosis is common, in which vesicular villi or necrotic villi may be found.

Most invasive hydatidiform moles are sensitive to chemotherapy and have a good prognosis. Even without chemotherapy, the tumor tissue in the metastatic lesion may regress naturally.

Due to the amount and degree of destruction of vesicular tissue, it can gradually transition from being very similar to benign hydatidiform mole to being very similar to choriocarcinoma, and can be divided into three types: Type 1, a large number of blisters can be seen with the naked eye, and the morphology is similar to hydatidiform mole, but it has invaded the myometrium or blood sinusoids, and there is very little bleeding and necrosis in the nearby tissue. Type 2: Few to moderate blisters can be seen with the naked eye, tissue has hemorrhagic necrosis, trophoblast cells are moderately proliferative, and some cells are poorly differentiated. Type 3: The tumor is almost entirely necrotic tissue and blood clots. A few blisters can be seen with the naked eye, and some enlarged villi can only be found under a microscope. The trophoblasts are highly proliferative and poorly differentiated, and the formation is very similar to choriocarcinoma.

Patients with hydatidiform mole must maintain a good mood, pay attention to nutritional supply, and actively enhance their body's resistance to disease. After suffering from this disease, you are not allowed to have sexual intercourse. Even after recovery, you are not allowed to get pregnant. Good contraceptive measures must be taken within two years after treatment. In addition, about 10% of patients with this disease may develop malignant changes.