Can uterine fibroids cause obesity?

Uterine fibroids are a common disease among women's reproductive organs. Although it is a benign tumor, it will directly affect women's health. Once this disease occurs, you will feel extreme pain in your abdomen and bleeding in your vagina, so you must go to the hospital for surgery. However, if the uterine fibroids are relatively small, no treatment is required. However, uterine fibroids can cause obesity in women.

Causes of uterine fibroids:

(1) Endocrine functional tumors: Endocrine functional tumors are rare tumors, but according to the research statistics of Peking Union Medical College Hospital, endocrine functional tumors account for 7.5%. The gonadotropin function of the pituitary gland is abnormal, and ovarian granulosa cell tumor is also a tumor that continuously secretes estrogen.

(2) Obesity: In obese women, androstenedione secreted by the adrenal glands is converted into estrone by aromatase in adipose tissue. The more adipose tissue there is, the stronger the conversion capacity and the higher the estrone level in the plasma, thus causing a persistent estrogenic effect.

There is a certain amount of androgen in women's bodies. For obese women, too much fat will cause androgen in the body to be converted into estrogen, resulting in increased estrogen production. The amount of estrogen produced by obese women in this way is 2 to 5 times that of people with normal weight.

In addition, obesity can change the metabolic pathway of estrogen, producing more of the more biologically active product - estriol.

The female hormones produced by these two methods do not have cyclical activity like the estrogen secreted by the ovaries, and cannot induce ovulation. Menstruation may be sparse, spotty, or heavy. The high level of estrogen in the body acts for a long time without the opposition of progesterone, which can easily cause endometrial hyperplasia, leading to a series of women's diseases such as irregular menstruation and uterine fibroids.

Therefore, when uterine fibroids appear, they will cause obesity. This is because the estrogen in women's bodies is greatly affected, which will cause the estrogen in their bodies to increase, and even reach about twice the normal weight. Therefore, the weight will naturally increase, and the body shape will become more serious. It is necessary to treat uterine fibroids in time to return to normal weight.