What is Polycystic Ovarian Syndrome?

I believe that everyone is not familiar with bilateral polycystic ovary syndrome, and many friends have never even heard of this name. Yes, this has nothing to do with men, but it is closely related to their mothers and wives. But what exactly is PCOS? Will it cause serious harm to the body? Let’s take a look together below.

The cause of PCOS is still unclear, and the pathological mechanisms involved are very complex. It is generally believed to be related to dysfunction of the hypothalamus-pituitary-ovarian axis, adrenal dysfunction, genetics, metabolism and other factors.

1. Genetics

PCOS is an autosomal dominant, X-linked (sex-linked) inheritance, or a disease caused by gene mutation. The chromosome karyotype of most patients is 46,XX, and some patients show chromosome aberration or mosaicism such as 46,XX/45,XO/46,XX/46,XXq and 46,XXq.

2. Adrenarche hypothesis

PCOS originates from prepubertal adrenal disease, that is, when subjected to strong stress stimulation, the zona reticularis secretes too much androgen, which is converted into estrogen outside the gonads, feedback-induced disturbances in the GnRH-GnH release rhythm of the HP axis and an increase in the LH/FSH ratio, which subsequently causes increased ovarian androgen production, that is, the adrenal glands and ovaries jointly secrete more androgen, leading to hyperandrogenemia. Hyperandrogenism causes thickening of the ovarian capsule fibrosis, inhibits follicular development, and causes ovarian cystic enlargement and chronic anovulation.

Traditional Chinese medicine believes that this disease is mainly caused by kidney deficiency, phlegm and dampness, qi stagnation and blood stasis, damp heat in the liver meridians, etc., which lead to dysfunction of the kidney-tiangui-chongren-uterus axis, resulting in amenorrhea and infertility.

After reading the introduction we carefully prepared for you, I wonder if it is helpful to you. At the same time, the ovaries are one of the important organs of female friends. In addition to bilateral polycystic ovary syndrome, there are many other diseases. Therefore, in daily life, everyone should pay attention to keeping warm, eat regularly, exercise more, and go to the hospital for regular check-ups.