Why does septate uterus malformation occur?

Why does septate uterus malformation occur? I believe many people don’t understand this question and are very curious. In fact, it is not surprising for female friends to encounter such a problem, because there will always be some problems during pregnancy, such as mediastinal uterine malformation. Let us learn about it together.

The uterus is formed by the fusion of the two paramesonephric ducts. After the para-mesonephric ducts merge, the mediastinum in the middle is not absorbed, and the mediastinum divides the uterine body into two halves, but the appearance of the uterus is normal. This deformity is called "septate uterus." A uterus that is completely divided into two parts by a septum from the fundus of the uterus to the internal or external os of the cervix is ​​called a "completely septate uterus". A uterus with a septum starting from the fundus of the uterus that partially separates the uterine cavity is called an "incomplete septate uterus". A septate uterus may cause obstruction, miscarriage, etc.

Uterine malformation with recurrent miscarriage, also known as uterine malformation, is a congenital disease and the most common type of reproductive organ malformation. Some patients with uterine malformation may not have any conscious symptoms, and there are no abnormal manifestations in menstruation, sexual life, pregnancy, and childbirth, so they may not be discovered throughout their lives, or may be discovered occasionally during a physical examination. Patients with uterine septate can undergo hysteroscopy or abdominal surgery.

During the formation and differentiation of female reproductive organs, due to certain endogenous factors (such as nondisjunction of germ cell chromosomes, mosaicism, karyotype abnormalities, etc.) or exogenous factors (such as the use of sex hormone drugs, etc.), the differentiation and development of primitive gonads, fusion of the rudiments of the internal reproductive organs, duct cavification and development may change, leading to various developmental abnormalities. Abnormalities caused by incomplete development of the paramesonephric duct derivatives will lead to abnormal development of the uterus and fallopian tubes, such as absence of uterus, absence of vagina, rudimentary uterus, uterine hypoplasia, unicornuate uterus, etc., and fusion disorders of the paramesonephric duct derivatives will lead to developmental abnormalities such as double uterus, bicornuate uterus, saddle uterus and septate uterus.

That’s right, the above are some of the reasons why mediastinal uterine malformation occurs. I believe that after understanding it, you will have some understanding of why mediastinal uterine malformation occurs. So if you encounter such a thing in life, please don’t worry, go to a regular hospital for treatment. I believe that through treatment, your illness will recover soon.