Magnesium sulfate, a "one-drug-multiple-purposes" drug, is useful for both wet compresses and oral administration

Speaking of magnesium sulfate, I believe that obstetric nurses are not unfamiliar with it. As a magnesium-containing compound, magnesium sulfate can be described as "good quality and cheap". Whether it is wet compress, oral administration, or intravenous injection, it will have different effects. So, what are the "fancy" uses of magnesium sulfate? Today, let's talk about the 6 major clinical applications of magnesium sulfate.

1. Oral administration

1. Diarrhea

This is mainly because magnesium sulfate is difficult to absorb in the intestines, and will form high osmotic pressure in the intestines, thereby preventing the absorption of water and producing a cathartic effect. When catharsis, take 5-20g orally each time and drink 100-400ml of water at the same time. Of course, it can also be dissolved in water before taking.

2. Promoting bile secretion

This is mainly because magnesium sulfate can stimulate the duodenal mucosa, which then reflexively causes the gallbladder to contract, thereby promoting gallbladder emptying and producing a choleretic effect. When taking choleretic medicine, take it before meals or between meals, 3 times a day, 2-5g each time.

2. Topical medication

3. Reduce swelling and relieve pain

When applied externally with wet compresses, the concentration of magnesium sulfate is 50%, and each wet compress is applied for 30 minutes. This is mainly because high concentrations of magnesium sulfate can produce high permeability in the affected area, thereby quickly eliminating the inflammatory response of local tissues.

3. Injection

4. Treatment of pregnancy-induced hypertension and preeclampsia

Usually, when used for the first time, a loading dose of 2.5-4 g is required, which is then diluted with 20 mL of 25% glucose and injected slowly over 5 minutes, followed by maintenance by intravenous drip of 1-2 g per hour.

5. Treating premature birth

The administration and dosage for the treatment of premature labor are similar to those for the treatment of pregnancy-induced hypertension.

6. Treat convulsions in children

It is administered by intramuscular or intravenous injection at a dose of 0.1-0.15 g/kg body weight, and then diluted with 5-10% glucose injection to a 1% solution for intravenous drip.