When the weather is warm and cold in spring, various respiratory diseases are prevalent. Many people have various antipyretic and analgesic drugs at home. Once they have fever, headache, sore throat, and various pains all over the body, they will take some to relieve the symptoms. 67-year-old Ye Bo (pseudonym) is also one of them, but what he never expected was that because of his "habit" of taking painkillers, he would need to have part of his stomach removed. It is reported that apart from his old problem of gout, Ye Bo was in good health. Two months ago, when his gout attacked again, he took the initiative to double the dose of ibuprofen painkillers he usually took, and at most, he took 12 tablets a day. Less than a week later, Ye Bo had unbearable abdominal pain and told his son that he had been having bloody stools for four days. His family rushed him to the hospital. When he was admitted to the hospital, Ye Bo had already suffered from hemorrhagic shock. After various examinations, Ye Bo was diagnosed with acute gastric mucosal damage caused by excessive use of painkillers, which in turn led to gastrointestinal bleeding and endangered his life. The team of Chief Physician Gao Yuan and Deputy Chief Physician Yang Weili of the Department of Gastrointestinal Surgery of Zhejiang University First Hospital carried out an emergency partial gastrectomy to save him. Recently, Ye Bo has recovered and been discharged from the hospital and is eating normally. recently #Ibuprofen can you give me a clear explanation?# Rushed to Weibo hot search Some netizens said: "Ibuprofen never fights a battle it is not prepared for" Some netizens also said: No matter what happens, take some ibuprofen
Did you use it correctly? 1. Ibuprofen It is a nonsteroidal anti-inflammatory drug with analgesic, antipyretic and anti-inflammatory effects. It reduces prostaglandin synthesis by inhibiting cyclooxygenase , thereby alleviating tissue congestion and swelling caused by prostaglandins and reducing the sensitivity of peripheral nerve pain. In addition, it can also exert an antipyretic (commonly known as "fever reduction") effect by acting on the hypothalamic temperature regulation center . It is a children's antipyretic drug recommended by the US FDA, a recognized first-choice anti-inflammatory drug for children, and a commonly used drug for the treatment of mild to moderate pain . 02. Ibuprofen is not a universal painkiller Ibuprofen can relieve many types of pain, including headaches, joint pain, migraines , etc., but please note that if you blindly take painkillers when you encounter certain pains, it may delay the condition. The most dangerous of these is the pain caused by heart disease . When a heart disease attacks, it may cause toothache, back pain, shoulder pain, and chest pain . If the above happens, you should see a doctor as soon as possible, and avoid taking painkillers on your own, which will delay the best treatment time. 03. Precautions for taking ibuprofen Although ibuprofen is a good medicine, it still needs to be taken strictly according to the dosage and medication cycle, and it should not be overdosed or used for a long time. In principle, the maximum oral dose of ibuprofen for adults is generally 2.4g per day , and it must be taken once every 4 to 6 hours . Children's livers are not fully developed, so medication needs to be used with caution . It is most appropriate to take ibuprofen at a dose of 5 mg to 10 mg per kilogram of body weight, 3 times a day. For antipyretic use, continuous use should not exceed 3 days, and for analgesia, continuous use should not exceed 5 days. Notice: 1. Please avoid drinking alcohol or beverages containing alcohol during medication: drinking alcohol may increase the risk of gastrointestinal bleeding and serious cardiovascular side effects. 2. It is recommended to closely monitor blood pressure during medication: ibuprofen may induce or aggravate hypertension. 3. Please do not take other medicines containing antipyretic and analgesic ingredients at the same time . For example, some compound cold medicines may contain non-steroidal anti-inflammatory drugs. 04. What is the difference between "ibuprofen" and "ibuprofen extended release" There are differences in the efficacy of ibuprofen sustained-release capsules/tablets and ibuprofen capsules/tablets: 1. Ibuprofen capsules/tablets are mainly used to reduce fever; 2. Ibuprofen sustained-release capsules/tablets are mainly used to relieve pain, especially muscle pain caused by exercise, such as strain during exercise, muscle soreness caused by sudden exercise after long-term inactivity, etc. Suspensions and granules are mainly used for children (over 6 months old) because they are easy to swallow and contain a small amount of ibuprofen. Adult patients are more suitable for capsules and tablets. It should be noted that suspensions need to be shaken before use. 05. Adverse reactions of ibuprofen 1. A small number of patients may experience nausea, vomiting, stomach burning or mild indigestion, gastrointestinal reactions (manifested as vomiting blood, black stools, abdominal pain, abdominal distension, etc.) and bleeding, increased transaminase, headache, dizziness, tinnitus, blurred vision, mental tension, drowsiness, lower limb edema or sudden weight gain. 2. Rare rash, allergic nephritis, cystitis, nephrotic syndrome, renal papillary necrosis or renal failure, bronchospasm . If the above symptoms occur during medication, or when rash or other allergic reactions occur for the first time, please stop taking the medicine and seek medical attention. 06. Four groups of people should use ibuprofen with caution Ibuprofen is a commonly used antipyretic drug, but not everyone can take it. The following four groups of people should use ibuprofen with caution: ① Patients with severe coronary heart disease or history of heart failure; ② Patients with a history of severe gastrointestinal ulcers and bleeding; ③ Patients who need to use antiplatelet drugs and anticoagulants in combination for chronic disease treatment; ④Patients with severe renal insufficiency. These people can choose acetaminophen instead of ibuprofen, but the daily dose of acetaminophen should be controlled within two grams to ensure safety, especially during combined treatment with compound cold medicines. Notice: Antipyretic and analgesic drugs should not be taken at the same time! Some Chinese patent medicines contain Western medicine ingredients, such as Ganmaoling Granules, VC Yinqiao Tablets, etc., which all contain acetaminophen. It is not recommended to use Chinese patent medicines together with acetaminophen or antipyretic and analgesic drugs such as ibuprofen. If used together, duplication of medication or overdose may occur. Source: People's Daily Online, China News Service |
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