HPV quadrivalent vaccine three injection interval

When it comes to cancer, everyone is quite afraid of it, and cervical cancer is one of the most common cancers in women. But now there is a vaccine to prevent cancer, this vaccine is also called four-media vaccine. After women are vaccinated, the chance of getting cervical cancer can be greatly reduced. So, how long should the four vaccines be administered?

Women need to get three shots of the four-dose vaccine. After the first shot, the second shot should be taken two months later, and the third shot should be taken four months later. Female friends do not need to rush to get the second shot next month or this month after getting the first shot, as this will easily affect the actual effect of the vaccine.

The medical name of the quadrivalent vaccine is human papillomavirus vaccine. This vaccine is an American brand. It is more suitable for women aged 20 to 45. However, women who want to have children within one year and women who are pregnant are not suitable for immediate vaccination. In addition, if a woman is allergic to any ingredient in the vaccine, she should not get the IV vaccine.

Even if a female friend has received the quadrivalent vaccine, she does not need to take chances in her daily life and should undergo regular gynecological examinations. If a woman has developed the disease before receiving the vaccine, the vaccine will not be effective even if she has been vaccinated. The quadrivalent vaccine can only have a preventive effect, and it can only prevent four types of HPV viruses.

What is the appropriate age to get the HPV vaccine?

The US FDA and CDC recommend that both boys and girls aged 11-12 should be vaccinated basically. According to the laws and regulations of each state in the United States, this age can be adjusted, starting at 9 years old. If you have not been vaccinated at the age of 12, you can get vaccinated between the ages of 13 and 26. People aged 11-12 who have not yet started having sex can get the best immunity effect after vaccination. Whether a woman has a history of CIN, VIN or genital warts will not affect vaccination. The antigen response caused by vaccination is strongest in those who are vaccinated at the age of 9 and can last for 15 years. Overseas, the FDA has not approved the HPV vaccine for women over the age of 26, but for some patients, the vaccine is feasible (offlabel), and these women can still gain slight benefits after vaccination. In Hong Kong, China, the age limit for vaccination is 45 years old.

The older the age, the lower the antibody titer concentration after HPV vaccination. Compared with the 16-26 year old group, the antibody titer after 9-15 year olds vaccination can be twice that of the former group. This is not the key reason for obviously recommending vaccination for people over 26 years old. Because the human immune system is not fully developed under the age of 9, the HPV vaccine is not effective for people under the age of 9. Therefore, the HPV vaccine is not recommended for people under the age of 9.