Effects of thrombophilia on pregnant women

Thrombophilia refers to a disease condition in which venous thrombosis is prone to occur due to natural genetic or acquired secondary defects or secondary risk factors such as anticoagulants, coagulation factors, plasminogen, etc. in the body. So what is the impact of thrombophilia on pregnant women?

What effects does thrombophilia have on pregnant women?

A good pregnancy depends on an adequate blood supply to the fetal circulatory system, and the persistent and abnormally high blood coagulation function of thrombophilic patients can lead to a tendency of venous thrombosis in the fetal tissues, accumulation of free fatty acids in the interstitial spaces of the fetus and formation of small thrombi in the fetal blood vessels, reduced fetal semen injection, and insufficient blood supply to the fetus, which can lead to miscarriage, gestational hypertension, placental abruption, and oligohydramnios.

What impact does thrombophilia have on the fetus?

Pregnant women with thrombophilia are prone to fetal nutrient supply and demand imbalance due to insufficient fetal blood supply, resulting in fetal growth restriction, fetal distress, premature birth, fetal loss in early pregnancy, fetal death in late pregnancy, and the occurrence of hereditary thrombophilia in the fetus.

How does one get thrombophilia?

Thrombophilia can be divided into congenital hereditary and acquired secondary.

The occurrence of congenital hereditary thrombophilia is mainly related to the patient's own genetic genes, which refers to the thrombotic condition caused by gene mutations resulting in anticoagulant protein deficiency, coagulation factor deficiency, fibrinolytic protein deficiency or metabolic deficiency.

Acquired secondary thrombophilia refers to a condition in which venous thrombosis is very likely to occur due to the presence of secondary thrombosis risk sources or abnormalities in secondary anticoagulant proteins, coagulation factors, plasminogen, etc., and there are many causes of the disease.

The occurrence of congenital hereditary thrombophilia is mainly related to the patient's own genetic genes, which refers to the thrombotic condition caused by gene mutations resulting in anticoagulant protein deficiency, coagulation factor deficiency, fibrinolytic protein deficiency or metabolic deficiency.

Acquired secondary thrombophilia refers to a condition in which venous thrombosis is very likely to occur due to the presence of secondary thrombosis risk sources or abnormalities in secondary anticoagulant proteins, coagulation factors, plasminogen, etc., and there are many causes of the disease.