How long does it take for a miscarriage to occur if progesterone is low?

Progesterone is a kind of estrogen in women's body that helps them stay pregnant. It has an important influence on the growth and development of the fetus. Therefore, after a woman becomes pregnant, it is very necessary to check her progesterone level during her prenatal check-up. Many people ask how long it will take for low progesterone levels to result in miscarriage? Before answering this question, you must have a certain understanding of its standard value.

How long does it usually take for a miscarriage to occur if progesterone levels are low during pregnancy?

Progesterone is a hormone that can delay the shedding of the uterine membrane (IVF). Low progesterone levels may lead to miscarriage, and this condition is very common. If progesterone levels drop significantly during the first few weeks of pregnancy, it may cause miscarriage. However, for women who hope to delay pregnancy, injecting large doses of progesterone can help prevent ovulation. In addition, the thick fluid it produces will also block male sperm from reaching the uterus and bilateral fallopian tubes.

How to check progesterone value and common problems of progesterone value check:

The progesterone level test is done by extracting the expectant mother's venous blood. Since the composition of the progesterone level is not affected by meals, the progesterone level test does not require fasting. In addition, you can drink more water when testing the progesterone level. Generally, after checking in the morning, the results can be obtained at noon.

In the entire menstrual cycle of a normal non-pregnant woman, the estrogen level is the lowest before ovulation, begins to rise after ovulation, and reaches the highest level during the follicular phase. Before ovulation, the progesterone level in the blood should be less than 2 ng/ml, and after ovulation it should be higher than 5 ng/ml.

If you are pregnant, the estrogen level will initially remain at the level of the follicular phase, and when the embryo is produced, the growth hormone secreted by the embryo will immediately increase the progesterone level in the pregnant woman's body to 100-200 ng/ml, which is dozens to thousands of times that of a non-pregnant woman.

The high and low progesterone levels will affect the growth and development of the pregnant mother and the fetus, so it should not be ignored. If the progesterone level is found to be high or low, you must seek medical attention immediately. In addition to medication for low progesterone during pregnancy, you should also pay attention to eating more fresh fruits in your diet. For example, fresh fruits such as kiwi, red grapefruit, strawberry seedlings, etc., these can help women replenish the vitamin C and vitamin E in the body, and at the same time promote progesterone levels to reach normal levels.

Progesterone value during pregnancy:

1. Suppress frequent uterine contractions

Many people believe that progesterone levels can change the permeability of the uterine muscle cytoplasm to ions, causing the membrane to be in a hyperpolarized state, thereby reducing the fluid regulation of the uterine muscle and, at the same time, reducing the sensitivity of the uterine muscle to various stimuli (especially oxytocin). Therefore, the pregnant uterus is not prone to strong and progressive contraction, the test tube embryo will not be affected, and the pregnancy can be maintained. Therefore, progesterone values ​​are commonly used in clinical medicine to maintain pregnancy.

2. Maintain decidual reaction

Decidual cells are transformed from endometrial stromal cells and contain glycogen granules, which balance the supply and demand of nutrients for the blastocyst. Injection of "rabbit anti-mouse decidual blood cells" into pregnant mice can induce miscarriage, indicating the necessity of decidua for maintaining pregnancy. Removal of both uterus and ovaries from animals with pseudopregnancy decidual reaction can cause decidual necrosis and vaporization; administration of exogenous progesterone can prevent decidual degeneration. This shows that progesterone levels are essential for maintaining the decidual response.

3. Suppress immune response

The fertilized egg is a semi-allogeneic graft (Semiallograft), but why is the embryo not rejected by the pregnant mother's immune system when it implants? People have found that when some tumor cells are transplanted into the uterus of animals, only in animals injected with progesterone hormone will the tumor cells not be rejected and embed into the endometrium, indicating that progesterone hormone can suppress the immune response. It can also be said that during a normal pregnancy, the increase in progesterone hormone can prevent the test tube embryo from being rejected by the pregnant mother and maintain the pregnancy. If the progesterone value and growth hormone are insufficient, the test tube embryo will seem like a foreign body and will be resisted by the pregnant mother, leading to miscarriage.