What is the normal value of Down syndrome screening?

What is the normal value of Down syndrome screening?

Everyone needs to go to the hospital for a Down syndrome screening when they become pregnant. Down syndrome screening is very necessary. It can help us understand the growth and development of the fetus and see if there are any problems with the fetus. So how much is the Down syndrome screening result worth? Maybe many people are not very clear about it, so let me introduce it to you below.

How much is the Down syndrome screening result standard worth

1. The normal range of alpha-fetoprotein (AFP) is 0.7-2.5MOM. If it is higher than 2.5MOM, it is high risk.

2. The higher the hcg gonadotropin, the lower the free estriol (uE3) (generally ≤0.25MOM) and the higher the inhibin A (Inhibin A), the higher the chance that the fetus will suffer from Down syndrome.

The doctor will also enter the above four items together with the pregnant woman's age, weight, gestational age, etc. into the computer to estimate the risk factors of the baby having Down syndrome. If the probability indicated by the test result exceeds the normal standard value (1/270), the result is positive, indicating that the probability of the fetus being sick is relatively high and more detailed examinations are needed. However, the calculation methods of each hospital's outpatient department are not exactly the same, and the standards are also different. Some hospitals' outpatient standard values ​​are lower than 1/270, while others are lower than 1/380.

What is Down syndrome screening test?

Amniocentesis: extract the amniotic fluid of the pregnant woman, shape the somatic cells of the fetus in the amniotic fluid of the pregnant woman, and detect the sex chromosomes of the somatic cells (detect the 21 sex chromosomes of the fetus). Extraction of amniotic fluid: Take 20ml of amniotic fluid. The risks are possible infection, leakage of amniotic fluid, miscarriage, and the possibility of miscarriage (probability 1/1000). The success rate is 98/100 to shape the cells of the fetus that fall into the amniotic fluid. Detect the sex chromosomes of somatic cells (detect the 21 sex chromosomes of the fetus), with an accuracy of 100/100.

How much is the standard value of Down syndrome screening results? After reading the editor's introduction, do you have a better understanding of this issue? In daily life, everyone must pay more attention to rest. Regular prenatal examinations are very necessary. In addition to Down syndrome screening, pregnant women also have many other tests to do, and they must set goals.

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