Does breast cancer run in the family?

Does breast cancer run in the family?

Breast problems are issues that cannot be ignored in modern life. Breast diseases have very serious impacts. Usually, if a woman suffers from breast disease, she is likely to develop cancer, which is extremely harmful to her health. Breast cancer will leave marks in the genes, increasing the risk of cancer. Does breast cancer have a family history? Let's take a look at the explanation below.

Epidemiological surveys have found that 5% to 10% of breast cancer is familial. If one close relative has breast cancer, the risk of the disease increases by 1.5 to 3 times; if two close relatives have breast cancer, the incidence rate increases by 7 times. The younger the age of onset, the greater the risk of breast cancer among relatives.

Breast cancer has a clear familial genetic tendency.

Why is breast cancer hereditary?

Some patients develop breast cancer through specific genetic genes (BRCA1/BRCA2 genes) inherited from their parents. The structural or functional abnormalities caused by these genes make the risk of breast cancer in carriers much higher than the general population. Studies have shown that approximately 70-85% of BRCA1/BRCA2 gene mutation carriers will develop breast cancer in their lifetime. More than 25% of breast cancers in women under 30 are caused by a mutation in a single inherited gene.

High-risk groups:

1. Women with breast hyperplasia that has not healed for many years

Breast hyperplasia is a chronic disease. Although not every case of breast hyperplasia will turn into malignancy, the many connections between the two remind people of the importance of active health care and treatment.

2. Women who work night shifts

It has been reported that women who work night shifts are more likely to develop breast cancer because their bodies secrete less of an important hormone that inhibits breast disease when they work night shifts. Scientists have confirmed that when people sleep at night, the human body secretes a hormone called melatonin, which can inhibit the growth of breast tumors. However, if women do not rest on time and are instead exposed to strong light, the production of melatonin under ischemic conditions will be conducive to tumor growth, and the growth rate is about twice the normal rate.

3. Urban white-collar workers

Urban white-collar women, due to the accelerated pace of work and intense pressure, are very likely to experience depression such as anxiety, loneliness, depression, sadness, disappointment, and irritability. Long-term stimulation of negative emotions will disrupt the body's life rhythm and neuroendocrine system dysfunction, which will lead to an imbalance in the internal environment and a decrease in immunity. The amount of thymosin produced and released by the thymus will decrease, and the ability of lymphocytes and macrophages to monitor and phagocytose mutated cells in the body will decrease, making them prone to cancer.

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