What is hyperplastic endometrium

Because modern women often have high work pressure and irregular diet and rest, they may develop some physical diseases. The most common one is uterine disease. Long-term staying up late and excessive mental stress can cause uterine disease. After the occurrence of uterine disease, the patient's skin will become very poor, and even some spots will appear. Hyperplastic endometrium is a disease of the female reproductive organs. Let us learn about hyperplastic endometrium together.

Causes:

The causes of endometrial hyperplasia are not yet fully understood, but the following phenomena and facts indicate that long-term estrogen stimulation is the main cause of the disease. Anovulation may occur in adolescent girls, perimenopausal women, or in cases of disorder in a certain link of the hypothalamus-pituitary-ovarian axis, polycystic ovary syndrome, etc. The endometrium is continuously affected by estrogen for a longer period of time without the opposition of progesterone and lacks the transformation of the cyclical secretory phase, and is in a state of hyperplasia. In postmenopausal women receiving estrogen replacement therapy (ERT), endometrial hyperplasia was observed in 20% of women taking estrogen alone for 1 year. Endometrial hyperplasia has also been observed in postmenopausal women with advanced breast cancer who have received long-term tamoxifen (TAM). Tamoxifen has a weak estrogen-like effect.

Clinical manifestations:

1. Age

Atypical endometrial hyperplasia occurs in younger women. It can also occur in perimenopausal or postmenopausal women.

2. Menstrual status

Abnormal menstruation is one of the prominent symptoms of this disease. It is often manifested as irregular vaginal bleeding, infrequent menstruation or amenorrhea for a period of time followed by long-term heavy vaginal bleeding.

3. Fertility status

Long-term anovulation due to endocrine abnormalities reduces the fertility of such patients. The infertility rate in patients under 40 years old can reach 90%.

examine:

The diagnosis relies on endometrial histology. The sampling methods include: endometrial biopsy, dilation and curettage, vacuum aspiration, and hysteroscopy. Since atypical endometrial hyperplasia often presents as scattered or single focal lesions, the entire endometrium may have various degrees of hyperplasia at the same time, and taking only a few tissue biopsies cannot reflect all changes in the endometrium. For perimenopausal women with atypical endometrial hyperplasia found during hysterectomy, 30%-50% of them also have well-differentiated adenocarcinoma. Therefore, it is very important to obtain comprehensive endometrial tissue from the uterine cavity for pathological examination. Compared with simply taking a few pieces of endometrial tissue, dilation and curettage can scrape more comprehensive tissue, but some areas may still be missed because the curette does not reach, especially the two uterine horns and the uterine fundus. Negative pressure suction can make the endometrium shed more completely, and the diagnosis will be more comprehensive and reliable. Hysteroscopy can not only observe the condition of the endometrium from its appearance, but also perform curettage or negative pressure aspiration under direct vision, making the examination and diagnosis more detailed and comprehensive.

The above article describes in detail the hyperplastic endometrium. I believe that after reading this, friends will have a deeper understanding of uterine diseases. Patients should pay attention to their diet in daily life. They should eat light food and drink more soups to facilitate digestion and body absorption. They can do appropriate outdoor exercises. In addition, they should pay attention to their body cleanliness and wash and change their underwear frequently.