What is total human chorionic gonadotropin

The question I want to talk to you about today is: What is total human chorionic gonadotropin? Regarding total human chorionic gonadotropin, many people's understanding of it is limited to the fact that it is a thing for testing early pregnancy. However, except for doctors, perhaps few people know its specific meaning. No one knows whether it is harmful to the human body or whether it has any effect on the fetus. Let's take a look at total human chorionic gonadotropin.

Human choionic gonadotophin (HCG) is a glycoprotein hormone secreted by placental syncytiotrophoblast cells. It is composed of α and β subunits, 237 amino acids, and a molecular weight of 39kD. Its α subunit is similar to the α subunits of FSH, LH and TSH, and has immune cross-reaction. Its structural difference is mainly in the β subunit, which can be distinguished in terms of immune activity. Due to the strong specificity of β-HCG, using specific antiserum to test the β-HCG levels in blood and urine is a flexible and accurate method for diagnosing early pregnancy. The primary function of HCG is to promote luteinization, which means that the corpus luteum of the menstrual cycle is transformed into the corpus luteum of early pregnancy. Its mechanism of action is to bind to the luteal cell membrane receptors, activate adenylate cyclase, and promote the secretion of progesterone. In addition, HCG can affect the synthesis and secretion of steroid hormones in the ovaries, stimulate the placental trophoblast to produce progesterone, etc.

Normal value:

Serum: HCG＜50mU/ml; β-HCG＜20mU/ml.

The above is the relevant content about total human chorionic gonadotropin. I hope it can help everyone. If the total human chorionic gonadotropin is higher than normal, pregnant women should pay special attention and go to the hospital for examination. It is important to maintain a good mood during pregnancy. The fetus can feel the mother's mood. I wish all expectant mothers can give birth to a healthy baby safely.