What is the best way to treat amenorrhea?

Amenorrhea is a common symptom of gynecological diseases in women. There are many causes of amenorrhea, usually primary and secondary amenorrhea. The difficulty of treating amenorrhea caused by different causes varies. After experiencing amenorrhea, women are still quite worried and are looking for the best treatment method. So, what is the best way to treat amenorrhea? Let’s take a closer look below.

1. Treatment of the cause

Find the organic disease that causes amenorrhea and give appropriate treatment. For example, tuberculous endometritis is treated with anti-tuberculosis drugs. Patients with intrauterine adhesions should have their uterine cavity dilated and an IUD placed to prevent recurrence of adhesions. After the diagnosis of pituitary or ovarian tumors is confirmed, the treatment plan is determined based on the location, size, and nature of the tumor, and surgery, radiotherapy, chemotherapy, or other comprehensive measures may be selected.

2. Sex hormone replacement therapy

Hormone replacement therapy can be used for those with congenital ovarian dysplasia, or those with impaired or destroyed ovarian function leading to premature failure. Artificial cyclical therapy with sex hormones is generally used. After the application of sex hormones, periodic withdrawal bleeding similar to menstruation occurs, which on the one hand corrects the patient's physiological and psychological state, and on the other hand promotes a certain degree of development of reproductive organs and secondary sexual characteristics.

(1) Low-dose estrogen cyclical therapy promotes pituitary function and secretes luteinizing hormone, thereby increasing ovarian estrogen secretion and promoting ovulation.

(2) Sequential estrogen-progestin therapy works by inhibiting the hypothalamic-pituitary axis. Menstruation may resume and ovulation may occur after discontinuation of the drug.

(3) The effect of combined estrogen and progesterone therapy is to inhibit pituitary gonadotropin. Occasionally, there will be a rebound effect after discontinuation of the drug, which can lead to the resumption of menstruation and ovulation. Take oral contraceptives once a night, starting from the fifth day of menstruation, and continue for 22 days before stopping. The second course of treatment begins on the 5th day of the next menstrual period, for a total of 3 to 6 cycles.

(4) Inducing ovulation: For patients whose ovarian function has not failed and who desire to have children, hormones or their analogues can be used to induce ovulation: ① For patients with pituitary insufficiency, follicle-stimulating hormone (hMG) extracted from the urine of postmenopausal women can be used to promote the development of follicles and the secretion of estrogen. Combined use of human chorionic gonadotropin (hCG), which is similar to pituitary luteinizing hormone, can promote the maturation of follicles to lead to ovulation, and promote the formation and development of the corpus luteum. ② When sexual dysfunction occurs, the ovaries and pituitary gland respond normally, but the hypothalamus is insufficient or uncoordinated. In this case, chloramphenicol is used to promote the secretion of gonadotropin-releasing hormone in the hypothalamus to correct its function and induce ovulation.

The above is an introduction to the best methods for treating amenorrhea. I hope it will be helpful for women. Because there are many causes of amenorrhea, and the treatment methods required for amenorrhea caused by different factors are also different. Women must not blindly undergo treatment. They must find the cause in order to obtain the best treatment effect. After all, women must pay attention to it.