Can progesterone preserve pregnancy?

For women who are born with insufficient corpus luteum, is it a suitable choice to inject drugs such as corpus luteum copper to maintain pregnancy? So, what is the use of injecting progesterone to maintain pregnancy? Let's have a simple understanding and understanding of this issue. I hope the following points will be of some help to everyone! Next, the editor will explain in detail the use of injecting progesterone to maintain pregnancy. Let's take a look.

Definition of progesterone value

Progesterone, also known as corpus luteum, is abbreviated as "P" in English. It is also called progesterone, luteinizing hormone, progesterone, estrogen, progesterone or progesterone. It is a steroid hormone related to female menstrual cycle, pregnancy, and effects on test tube embryos of humans and other animals. It is produced by ovarian gestational progesterone in the early pregnancy. During pregnancy, progesterone is the key hormone supporting the early development of the fetus. A high concentration of progesterone has a significant calming effect on the enlarged uterus and is also very important for support in early pregnancy.

During pregnancy, hCG stimulates corpus luteum to produce progesterone levels; from 7 to 9 weeks, it gradually connects to embryo formation, also known as corpus luteum embryo transfer; from 10 to 11 weeks, the progesterone levels continue to rise during embryo formation, at this time the trophoblasts of the embryo take over corpus luteum to produce estrogen and maintain pregnancy. The progesterone level test during pregnancy is mainly used to understand the function of progesterone, whether the uterus and ovaries ovulate, and to understand the pregnancy status.

What is the use of progesterone injection to maintain pregnancy

Progesterone copper is an estrogen drug whose functions include: promoting the growth and development of the uterine wall during pregnancy to facilitate the implantation of the embryo in vitro fertilization; promoting the weakening of the muscles of the pregnant uterus and reducing its ability to move, thereby weakening its ability to respond to external stimuli, and reducing the sensitivity of the pregnant uterus to oxytocin compounds, which is beneficial to the combination of sperm and egg in the uterus. Therefore, in many cases, lutein copper is the preferred drug for treating threatened abortion, but it is only suitable for threatened abortion caused by insufficient progesterone metabolism and estrogen deficiency, and is ineffective for threatened abortion caused by non-luteal insufficiency. Therefore, before use, you must find out whether the pregnant woman is deficient in estrogen and do not use it indiscriminately. Pregnant women should have their blood estrogen concentration tested before taking the medicine. If threatened abortion occurs within 3 months of pregnancy, it is mostly related to insufficient corpus luteum function, and the use of corpus luteum copper is reasonable; after 3 months of pregnancy, the embryo can metabolize progesterone and no longer relies on the metabolism of the ovarian corpus luteum. Therefore, miscarriage at this time is mostly caused by other reasons, and the use of corpus luteum copper will have no effect.

The causes of threatened abortion are very complicated. In pregnant women, in addition to luteal insufficiency, there are also reasons such as thyroid deficiency, infectious diseases, high fever, severe anemia, malnutrition, exposure to radioactive substances, toxic substances, and reproductive malformations such as double uterus and uterine fibroids, which can also cause miscarriage. The most important factor in the fetus is chromosomal abnormality. 50% to 70% of early miscarriages are caused by chromosomal abnormalities in test tube embryos. For fetuses in this condition, any pregnancy-stabilizing drugs will be useless.

During the process of luteal copper to maintain pregnancy, natural estrogen should be used, and it is not dangerous to use it in the case of insufficient progesterone levels. The dosage and frequency of use can be determined according to the actual situation of the pregnant woman. A more scientific method is to determine the dosage based on the blood cell progesterone level: if the progesterone value is significantly lower than the standard value, a large dosage should be used; if the progesterone value is not too low, a low dosage can be used. Natural progesterone Chinese medicine preparations can be used to maintain pregnancy, such as intramuscular progesterone injection, oral dydrogesterone, and progesterone capsules. There are currently no reports in medical literature of natural progesterone preparations causing fetal malformations; but Angong Progesterone Tablets cannot be used, because Angong Progesterone Tablets are estrogen in chemical herbal preparations, which can easily cause male characteristics in female fetuses.