What is the normal thickness of the double inner membrane?

Many of you may not know much about this double-layer endometrium. In fact, the thickness of the endometrium is different at different times. If the thickness of the endometrium of some women is not normal, it may be due to endometrial hyperplasia, which can easily induce the occurrence of endometrial cancer.

What is endometrial double layer thickness?

The normal thickness of the endometrium is different at different stages of the menstrual cycle. If the endometrium is thick, menstruation will be painful and the fertilized egg will not be easy to implant. Generally speaking, the normal thickness of the endometrium is 0.2-1.0 cm. During menstruation, the functional layer of the endometrium is shed and the basal layer is preserved. The proliferative phase is from the 6th to the 14th day of menstruation, and the normal thickness of the endometrium is about 1-3mm. The secretory phase is from the 15th to the 28th day of the menstrual cycle, and the thickness of the endometrium is about 5-7mm. However, the thickness of the endometrium of some women is obviously inconsistent with the normal thickness after examination. Then the thin hyperplasia of the endometrium can lead to female infertility and some may even cause endometrial cancer.

Endometrial hyperplasia is a method for treating endometrial hyperplasia. It can also be used to treat endometrial hyperplasia and endometrial polyps. The main functions of Endometrial Elimination Grass are to promote blood circulation and remove blood stasis, disperse nodules and eliminate symptoms, and to regulate Qi and relieve stagnation, and strengthen the body as auxiliary functions, so as to eliminate the symptoms of irregular menstruation, inhibit endometrial growth, and restore normal uterine function. The normal cyclical changes in the thickness of the endometrium can be divided into three phases: 1. Proliferative phase: the 5th to 14th day of the menstrual cycle, which is equivalent to the stage of follicle maturation. Under the action of estrogen during the follicular phase, endometrial glands and interstitial cells proliferate. The proliferative stage is divided into three stages: early, middle and late.

The thickness of the endometrium changes cyclically.

1. Proliferative stage

Around the 5th to 9th day of the menstrual cycle, the endometrium is very thin, the glands are sparse, the glandular ducts are narrow and straight, and the glandular cavity surface is flat.

During the 10th to 14th day of the menstrual cycle, the endometrium becomes thicker and wavy, the glands and stroma proliferate significantly, and the number of glands begins to increase.

2. Secretory phase

On days 15 to 19 after ovulation, from day 1 to 5, the endometrium continues to increase and the glands further expand and bend.

Around the 20th to 24th day of the menstrual cycle, which is 6 to 10 days after ovulation, the endometrium shows a high degree of secretory activity, and the curvature and expansion of the glands reach a peak.

3. Late secretory phase

The thickness of the endometrium is about 5 to 6 mm.

Causes of endometrial thickening

(1) No ovulation

Anovulation may occur in adolescent girls, perimenopausal women, those with a disorder in a certain link of the hypothalamus-pituitary-ovarian axis, polycystic ovary syndrome, etc., causing the endometrium to be continuously affected by estrogen for a longer period of time, without progesterone to counteract it, lacking the transformation of the cyclical secretory phase, and being in a state of hyperplasia for a long time. In patients with atypical endometrial hyperplasia under the age of 40, except for focal atypical hyperplasia, more than 80% of the other endometrium has no secretory phase; 70% of the basal body temperature measurement results are monophasic. Therefore, most patients do not ovulate.

(2) Obesity

In obese women, androstenedione secreted by the adrenal glands is converted into estrone by aromatase in adipose tissue; the more adipose tissue there is, the stronger the conversion capacity is, and the higher the level of estrone in plasma is, resulting in a sustained estrogenic effect.

(3) Endocrine functional tumors

Endocrine functional tumors are rare tumors, but in research statistics, endocrine functional tumors account for 7.5%. The gonadotropin function of the pituitary gland is abnormal, and ovarian granulosa cell tumor is also a tumor that continuously secretes estrogen.