What is the reason for large-scale shedding of the endometrium during menstruation?

Women will experience endometrial shedding during menstruation. Generally, this is a normal phenomenon. However, if large chunks of endometrium are shed during menstruation, it needs to be taken seriously. Large chunks of endometrial shedding usually lead to increased bleeding, which is mostly caused by uterine stimulation. It is likely that you have a uterine disease. It is best to go to the hospital for an examination and receive symptomatic treatment based on the results.

Causes of large shedding of endometrium during menstruation

First, because of excessive endometrial hyperplasia, large chunks of endometrium will fall off.

Second, due to insufficient secretion of fibrase in the body, the endometrium during the secretory phase cannot be dissolved, so it falls off in large chunks. When large pieces of endometrium are shed, the uterus will experience spasmodic contractions in order to expel them, and the patient will clinically experience severe lower abdominal pain. It is recommended to start taking brown sugar ginger water orally before menstruation, and pay attention to keeping warm during menstruation.

Causes of endometrial shedding during menstruation

The entire female reproductive system is controlled by the sex hormones secreted by the ovaries. The ovarian cycle causes a series of cyclical changes in the female sexual organs, especially the cyclical changes in the endometrium. During the menstrual period, which is the 1st to 4th day of menstruation, the increase of progesterone and the withdrawal of estrogen cause the spongy functional layer of the endometrium to disintegrate and fall off from the basal layer. Within 24 hours before menstruation, the endometrial spiral arteries contract and relax rhythmically, followed by gradually increasing vasospasm and contraction, leading to ischemia, necrosis, exfoliation, and shedding of the distal vascular walls and tissues, and endometrial fragments and blood flow out of the vagina, causing menstruation.

What causes endometrial shedding?

The shedding of the endometrium is primarily due to a decrease in estrogen and progesterone levels before menstruation. When estrogen and progesterone levels decrease, the endometrium loses the support of high hormone levels, so exfoliative bleeding occurs. Under normal circumstances, the endometrium changes with the menstrual cycle, and this change is mainly related to changes in the levels of estrogen and progesterone in the patient's body. After the patient's menstruation ends, the FSH level will be very high, so it will stimulate the patient's ovaries to develop follicles.

As the follicles grow, the patient's estrogen level increases, which stimulates the patient's endometrium to proliferate. After a woman ovulates, her estrogen levels drop and her progesterone levels rise. Progesterone can inhibit the excessive proliferation of the endometrium, causing the endometrium to transition from a proliferative phase to a secretory phase, mainly in preparation for the implantation of the fertilized egg. When the patient fails to conceive, the estrogen and progesterone levels will drop, so the patient's endometrium will be shed and menstruation will occur.