Side effects of medroxyprogesterone

Lutein is a natural estrogen secreted by the corpus luteum of the ovary. It has a significant effect on the shape of the uterine wall stimulated by estrogen in the body and is essential for maintaining pregnancy. Medroxyprogesterone is a synthetic corpus luteum copper, generally used for threatened abortion or habitual abortion, functional amenorrhea or abnormal uterine bleeding, dysmenorrhea, uterine wall adenocarcinoma, endometriosis, etc.

The efficacy of progesterone

Lutein is a natural estrogen secreted by the corpus luteum of the ovary. It has a significant effect on the shape of the uterine wall stimulated by estrogen in the body and is essential for maintaining pregnancy. Clinically, it is commonly seen in threatened abortion, habitual abortion, uterine wall movement, multifunctional abnormal uterine bleeding, dysmenorrhea, amenorrhea caused by ovarian hypoplasia or reactive rashes caused by amenorrhea. It can also be administered vaginally instead of orally, especially for patients with liver disease.

Medroxyprogesterone is a synthetic corpus luteum copper, generally used for threatened abortion or habitual abortion, functional amenorrhea or abnormal uterine bleeding, dysmenorrhea, uterine wall adenocarcinoma, endometriosis, etc. If used in larger doses, it can have the effect of a highly effective contraceptive injection. It can also treat the pregnancy caused by the lack of estrogen and estrogen in the uterine wall, and slowly replenish estrogen and progesterone through artificial means. Especially estrogen. This will ensure that the uterine wall continues to thicken, so that the uterine wall can be tightly attached to the endometrium, allowing the produced sperm and eggs to combine with good embryo implantation space. It can also delay menstruation.

What is medroxyprogesterone

Medroxyprogesterone acetate is also known as medroxyprogesterone acetate. Lutein copper is a natural estrogen secreted by the corpus luteum of the ovary. It has a significant histological effect on the uterine wall stimulated by estrogen in the body. It is essential for maintaining pregnancy and is mainly used for fetal maintenance treatment.

Implementation suggestions: Medroxyprogesterone acetate is an estrogen drug. The specificity of estrogen is 20 to 30 times that of luteal copper when injected subcutaneously. It is highly effective when injected intramuscularly and can be used to treat multifunctional bleeding, amenorrhea, and endometriosis caused by growth hormone imbalance.

Usage and dosage:

1. Threatened abortion: take orally 4-8 mg once, 2-3 times a day. For habitual abortion, take 10 mg per day in the first 3 months, 20 mg per day after the 4th to 4.5 months, and finally reduce and stop taking the medicine.

2. Menstrual pain: Starting from the 6th day of the menstrual cycle, take 2-4 mg once a day for 20 consecutive days; or starting from the 1st day of the menstrual period, take 3 times a day for 3 consecutive days.

3. Functional amenorrhea: take 4-8 mg per day and use for 5-10 days.

Side effects of medroxyprogesterone

First of all, patients with thrombophlebitis, venous thrombotic occlusive disease, severe liver dysfunction, hypercalcemia, missed abortion, abnormal uterine bleeding, pregnancy or allergic reaction to this product should not use this drug.

Its side effects include:

1. Similar to other progesterone drugs, breast pain, galactorrhea, amenorrhea, cervical erosion or cervical metabolic changes and masculinization of male breasts may occur.

2. Mental level: nervousness, insomnia, drowsiness, fatigue, and dizziness.

3. Skin and mucous membranes: Allergic symptoms ranging from itching, hives, angioedema to systemic rash and unprotected reactions have been reported. In very rare cases, acne, baldness or excessive hair growth have been reported.

4. Digestive tract: nausea and indigestion, especially in large quantities.

5. Human body: Sometimes it can cause breast pain and abdominal distension.

6. It may also cause similar renal aldosterone reactions and hypercalcemia reactions, and there are occasional reports of obstructive jaundice.

Frequently asked questions about Medroxyprogesterone

1. This drug must be used under the guidance of an experienced physician. If venous thrombosis symptoms such as migraine, decreased vision, diplopia, etc. occur due to the drug's increased coagulation function, the drug should be discontinued immediately.

2. Some women experience symptoms such as non-menstrual bleeding. If bleeding occurs, you can take 0.05-0.1 mg of ethinyl estradiol according to the amount of bleeding. Take it for 3 consecutive days to promote blood circulation. Use with caution in patients with liver disease or nephritis.

3. It has a certain androgenic effect. Long-term use during pregnancy can cause female fetuses to have male characteristics.

4. Patients with venous thrombosis, liver and kidney dysfunction, breast tumors and miscarriage are prohibited from using this product.

5. When continuing to use large doses of MPA for treatment, you should pay attention to whether there are symptoms of hypertension, hypokalemia, hypercalcemia, etc. If these symptoms occur, you should adjust the medication.

6. This product may cause a certain level of blood retention. People with epilepsy, migraine, asthma, heart failure or renal insufficiency should be observed carefully when using this product.

7. Patients with a history of depression need to be carefully observed, and if the depression attack is severe, medication should be discontinued. Some patients have reduced glucose tolerance when using estrogen, so diabetics should use it with caution.