Can endometrial hyperplasia lead to pregnancy?

Endometrial hyperplasia can actually affect pregnancy for patients. The thickening of the endometrium changes with the ovarian cycle, so the changes are quite obvious. Female friends must pay attention to this aspect. If treatment is delayed, it may seriously lead to infertility.

1. Will endometrial thickening affect pregnancy?

The thickening of the endometrium follows the cyclical changes of the ovaries, and other parts of the reproductive organs also undergo corresponding cyclical changes. Among them, the changes in the endometrium are particularly significant, including the stages of endometrial proliferation, secretion, shedding and repair. If female friends do not pay attention to early treatment and prevention and delay treatment, it will lead to serious consequences and even cause infertility.

Treatment of endometrial thickening

1. Drug treatment

The principles are standardized medication, long-term examinations, regular testing, and timely assisted pregnancy. Types of medication: ① The ovulation-inducing drug clomiphene is taken once a day from the 5th to the 9th day of the cycle. If necessary, the medication period can be extended by 2 to 3 days. ② Progestin drugs: They vary according to the degree of endometrial atypicality. Mild atypical hyperplasia can be treated with intramuscular injection of progesterone, starting on the 18th or 20th day of the cycle, and the drugs should be taken for 5 to 7 days. Patients with moderate and severe atypical hyperplasia should use medroxyprogesterone continuously for a course of 3 months. After each course of treatment, a curettage or removal of endometrial tissue should be performed for histological examination. Depending on the response to the drug, the patient can choose to stop treatment or increase or decrease the dosage of the drug as appropriate. An intrauterine ring can also be placed.

2. Surgical treatment

Curettage and aspiration is not only an important diagnostic method, but also one of the treatment methods. Because local lesions can also be removed through curettage. Patients with atypical endometrial hyperplasia who are over 40 years old and have no fertility requirements can undergo hysterectomy once diagnosed. However, for patients with hypertension, diabetes, obesity or advanced age who have poor tolerance to surgery, drug treatment may be considered under close follow-up monitoring. Young patients who have not responded to drug treatment, whose endometrial hyperplasia continues or worsens or is suspected of having developed cancer, whose vaginal bleeding cannot be controlled by curettage and drug treatment, and whose condition recurs after delivery, may all consider surgical removal of the hysterectomy.