We all say that pregnant women eating more fish is the best help for their children, because the babies born in this way may be very smart. However, if pregnant women accidentally get a fish bone stuck in their throat while eating fish, and this causes throat inflammation and discomfort, can they use certain anti-inflammatory drugs to help relieve the symptoms at this time? But will anti-inflammatory drugs cause adverse effects on the baby in the belly? 1. Available: Penicillin is the first choice. Penicillin is minimally toxic to humans. Commonly used ones include ampicillin, carbenicillin, and cephalosporins (such as cephalosporin, etc.). 2. Use with caution: Aminoglycosides include streptomycin, kanamycin, gentamicin, and amikacin. They should be used with caution because they can damage fetal renal function and hearing. If it is necessary to use it, it should be used in small doses and for a short course of treatment. 3. Disable: ① Chloramphenicol is detoxified by combining with glucuronic acid in the liver and then excreted through the kidneys. Because the fetal liver enzyme system is not perfect and the kidneys have poor excretion capacity, the use of chloramphenicol can easily cause "gray baby syndrome", which can damage the fetal hematopoietic system and cause fetal thrombocytopenic purpura, granulocytopenia or aplastic anemia. Therefore, it is forbidden for pregnant women to use chloramphenicol. ②Tetracycline: It is a typical teratogen. In the early pregnancy, it chelates with calcium salts to prevent calcium salts from entering cartilage and bones, leading to fetal limb hypoplasia and microlimb deformities; in the second pregnancy, it inhibits fetal bone growth, leading to congenital cataracts, abnormal development of deciduous teeth, and yellow deciduous teeth; in the late pregnancy, it causes tetracycline deposition in deciduous teeth and bones, making them yellow, and can cause fatty degeneration of the liver in pregnant women, so it is forbidden for pregnant women. ③ Nidazole (also called metronidazole) is prohibited for use by pregnant women because it has teratogenic effects on the fetus. ④ Iodamine drugs, such as SMZ, can easily pass through the placenta into the fetus, compete with the bilirubin in the fetal blood for plasma protein binding sites, increase the free bilirubin in the blood, and easily cause kernicterus, so they are prohibited for use by pregnant women. In addition, the antifungal drug griseofulvin is contraindicated in pregnant women because of its teratogenic effects. There is still controversy as to whether pregnant women can use nystatin and clotrimazole. ?? In short, if pregnant women must use antibiotics, they should use them. Otherwise, if the disease is not treated, the disease will also affect the fetus. However, they must master the period, dosage and route of administration and avoid abusing antibiotics. |
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