Does low estrogen levels affect ovulation?

When a girl has her first menstruation, her ovaries begin to develop, the body's estrogen produces menstruation, and ovulation begins. As age increases, the body's organs mature. However, estrogen is associated with a variety of factors, such as gynecological diseases, diet, and medication. Changes in estrogen can develop into a variety of diseases. Patients should observe their physical discomfort symptoms to determine whether the abnormality requires treatment. So, will low estrogen levels in women affect ovulation?

Low estrogen levels can affect ovulation. Estrogen is a female hormone produced by the ovaries and placenta. The adrenal cortex also produces small amounts of estrogen. After female children enter puberty, their ovaries begin to secrete estrogen to promote the development of the vagina, uterus, fallopian tubes and ovaries themselves. At the same time, the endometrium proliferates and produces menstruation. Estrogen can also promote the accumulation of subcutaneous fat and a fuller body; cause breast hyperplasia, darker nipples and areolas, and produce sexual desire; promote the retention of sodium and water in the body and the deposition of calcium in the bones, etc.

Estrogen is mainly derived from the follicular theca cells and granulosa cells. During follicular development, LH first stimulates the follicular membrane to secrete testosterone, which is then converted into estradiol by granulosa cells under the stimulation of FSH, which is the "dual-cell dual-gonadotropin action mode." In addition, it is also secreted by the adrenal cortex, placenta and testicles of male animals. The definition of estrogen here is estradiol. After ovarian failure, estradiol drops sharply, causing estradiol deficiency diseases such as menopausal syndrome.

When the follicles begin to develop, they only secrete a small amount of estrogen; by the 7th day of menstruation, the amount of estrogen secreted by the follicles increases rapidly, reaching a peak before ovulation and decreasing slightly after ovulation. About 1 to 2 days after ovulation, the corpus luteum begins to secrete estrogen, causing the estrogen level in the blood circulation to gradually increase (Note: this is the effect of luteinizing hormone). When the corpus luteum matures about 7 to 8 days after ovulation, the second peak of estrogen in the blood circulation is formed, which is lower than the first peak before ovulation.

Regardless of their source, any substance that has estrogen effects is called estrogen. Not to mention estrogen, some of its metabolites (such as equilin, equilenin, etc.) and their substitutes (such as ethyl estradiol, etc.), the estrane-based C18 steroids, all originally came from animals, but some of them are also found in places that have nothing to do with animals, such as coconut fruits and asphalt.

In addition, there are also substances that do not contain steroid structures and can be obtained completely through synthesis as estrogen substances, such as ethinyl estradiol, hexestrol, and benzestrol, which are derivatives of 1,2-diphenylethylene, and doisynolic acid substances whose D ring is opened by oxidation of estrogens, or homoestrone whose D ring is converted into a hexacyclic ring. The reasons why these structures are different but have the same function are not yet clear. Methods for identifying estrogen include the Allen-Doisy test and the uterine weight method. Because of differences in test methods and methods of hormone administration, the results obtained may not be the same. The action (keratinization of the vaginal epithelium) caused by 0.1 microgram of pure estrogen is used as one international unit (IU). For benzoate preparations, 0.1 μg of estradiol benzoate was used as the standard.

Will low estrogen levels in women affect ovulation? After reading the article above, we can judge that low estrogen levels in women can affect ovulation, and in severe cases, infertility can occur directly. Women of childbearing age should pay attention to this issue. If they have not gotten pregnant for a long time without taking contraceptives, they should go to the hospital for examination. Of course, infertility diseases should be ruled out, but as long as the patient is examined, the disease can be identified, and treatment can be used to cure the disease and ovulation will return to normal.