What are the causes of endometrial polyps?

In daily life, some middle-aged women always have irregular menstruation or vaginal bleeding, which makes them particularly worried. Later, after the doctor's diagnosis, they find out that they are suffering from endometrial polyp hyperplasia. Many women find it very strange. They usually pay attention to it. Why do they get this disease? What is the reason? So let me introduce to you the causes of endometrial polyp hyperplasia.

(1) Anovulation: Anovulation may occur in adolescent girls, perimenopausal women, disorders in certain links of the hypothalamus-pituitary-ovarian axis, polycystic ovary syndrome, etc., causing the endometrium to be continuously affected by estrogen for a long time without progesterone to counteract it, lacking the transformation of the cyclical secretory phase, and being in a state of hyperplasia for a long time. Among 41 patients with atypical endometrial hyperplasia under the age of 40 at Peking Union Medical College Hospital, more than 80% of their endometrium had no secretory phase except for focal atypical hyperplasia; 70% of the basal body temperature measurements were monophasic. Therefore, most patients do not ovulate.

(2) Obesity: In obese women, androstenedione secreted by the adrenal glands is converted into estrone by aromatase in adipose tissue. The more adipose tissue there is, the stronger the conversion capacity and the higher the estrone level in the plasma, thus causing a persistent estrogenic effect.

(3) Endocrine functional tumors: Endocrine functional tumors are rare tumors, but according to the research statistics of Peking Union Medical College Hospital, endocrine functional tumors account for 7.5%. The gonadotropin function of the pituitary gland is abnormal, and ovarian granulosa cell tumor is also a tumor that continuously secretes estrogen.

(4) Estrogen replacement therapy (ERT): During the perimenopause or postmenopause period, due to estrogen deficiency, there are menopausal syndromes, and at the same time, there may also be osteoporosis, abnormal lipid metabolism, cardiovascular changes, and even changes in brain cell activity. Therefore, ERT? has been gradually widely used and has achieved good results. However, ERT, which contains estrogen alone, can stimulate endometrial hyperplasia. Using estrogen alone for one year can cause endometrial hyperplasia in 20% of women (Woodruff 1994). The use of ERT is often continuous for years, or even for a lifetime. If it is not used in combination with progestins for a long time, severe endometrial hyperplasia or even endometrial cancer will occur.

The above is an introduction to the causes of endometrial polyps. I believe that after reading the article, women will have a better understanding of the causes of this disease and can better prevent it in daily life. Of course, women should also pay more attention to regular life and regular diet in their daily lives, avoid eating spicy and irritating foods, and eat more vegetables and fruits, which will be of great help to the health of the body.