What should I do if the follicle develops too large?

Women often experience some abnormalities in the development of follicles due to various reasons. For example, if the follicles are found to be too large, it will have a great impact on women's normal conception. Therefore, when abnormal follicular development is found, effective methods should be taken in time for treatment. There are many methods currently used to treat follicular dysplasia. The following editor will introduce several commonly used methods every other day.

If the follicles are underdeveloped, forcibly using ovulation-inducing drugs in a short period of time to force ovulation will cause the eggs to be released, but they will be immature and therefore cannot lead to normal conception. Even if the sperm and egg combine, miscarriage, stillbirth, etc. are likely to occur.

For those with poor follicular development, the most commonly used method is to supplement hormones and use some ovulation-stimulating drugs to help ovulation. Judging from the clinical results achieved so far, the efficacy is very obvious.

But it is worth reminding that if the follicles fail to rupture after several months of using ovulation-stimulating drugs, you may need to do in vitro fertilization.

Only when the follicles are fully developed and function well can the eggs released be mature and healthy. If a woman faces the problem of poor follicular development, the editor recommends that she go to the hospital for relevant examinations and receive treatment in time.

If the follicles are poorly developed, the eggs discharged are unhealthy and there is no chance of fertilization, which directly affects conception.

What should I do if the follicles do not develop well? The main treatments of Western medicine are: clomiphene therapy, CC-estrogen therapy, and CC-HCG therapy.

Clomiphene therapy

This drug has weak estrogenic and anti-estrogenic effects. Its main site of action is in the thalamus. CC and E2 competitively bind to the estrogen receptors in the thalamic cytoplasm to form a receptor complex. Due to the difference in the three-dimensional structure of CC and E2, this combination can no longer exert the biological effects of estrogen.

CC—Estrogen Therapy

To change the quality and quantity of cervical mucus and facilitate the passage of sperm, after CC administration, diethylstilbestrol 0.5 mg/d or Premarin 2.5 mg/d are given for a total of 7 days. CC-progesterone therapy: To treat luteal insufficiency, progesterone 20 mg/d can be given intramuscularly for 10 consecutive days starting on the second day of the high temperature phase, or progesterone acetate 10 mg/d can be taken orally.

CC-HCG therapy

This infertility treatment method is suitable for cases where the follicles can mature after CC, but due to abnormal positive feedback mechanism, there is no LH peak and ovulation occurs. The time of HCG administration is the most important. Generally speaking, when the largest follicle is more than 22mm, HCG 5000-10000U is injected intramuscularly, and luteal support or luteal replacement therapy should be given after ovulation.

Therefore, when female friends find that their menstruation is abnormal, it is best to go to the hospital for examination in time. If abnormal follicles are found, they should use some of the methods introduced above for treatment in time. You can also choose a method that suits you under the guidance of a lifetime based on your physical condition and disease characteristics.