How to interpret the results of breast cancer immunohistochemistry

How to interpret the results of breast cancer immunohistochemistry

There are three unique features in breast cancer immunohistochemistry reports: 1. ER is also known as estrogen receptor. It is better to be positive, and the more minus signs, the better. 2. PR is also called estrogen protein kinase. A positive result is relatively better than a negative result. 3. HER2 (also known as human epidermal growth factor kinase 2) expression increases in breast cancer, which is directly proportional to the metastasis and stage of breast cancer. Therefore, the higher the expression, the relatively worse the prognosis. If the above three indicators are all negative, it is clinically called triple-negative breast cancer. The prognosis of this type of breast cancer is relatively poor because there is currently a lack of effective drug treatment.

Several reasonable treatment methods for breast cancer

Breast cancer is a disease that threatens women's life and health. As a woman, you should pay more attention to your own health and do regular physical examinations. There are many treatments for breast cancer, including traditional treatments and microbial treatments. Generally, a variety of treatments and methods are used in the treatment process in order to achieve better results.

1. Surgical treatment: Surgical treatment is still one of the main treatment methods for breast cancer. Its goal is to avoid surgical damage as much as possible, reduce the scope of removal, and preserve the breast shape to the greatest extent. Includes breast-conserving surgery and sentinel lymph node biopsy. Among them, breast-conserving surgery is mainly used for patients with early-stage breast cancer. Breast-conserving surgery with a safe resection margin plus postoperative radiotherapy and chemotherapy has the same effect as total mastectomy, but the patient's breast shape is not damaged.

2. Tumor radiotherapy: Tumor radiotherapy is an important component of breast cancer treatment, but it is less used than surgical treatment because its equipment is difficult to achieve the goal of completely eliminating the tumor. It is often combined with other treatment methods for comprehensive treatment.

3. Endocrine therapy: Endocrine therapy for breast cancer is the most complete and effective endocrine therapy for tumors, but it is non-curative. Its treatment goal is to reduce the level of estrogen in the body's circulation and tumors to reduce the growth of tumor cells.

4. Chemotherapy: Chemotherapy refers to the treatment with chemical drugs, which is the main treatment method for breast cancer. The purpose of chemotherapy is to completely eliminate the tumor cells remaining in the body after surgery, so as to improve the cure rate and reduce the occurrence and migration of tumor cells after surgery.

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