Female kidney disease patients who meet these conditions can become pregnant, come in and take a look!

In the past, it was rare for patients with chronic kidney disease to become pregnant, but with the improvement of medical conditions and the popularization of physical examinations, more and more kidney disease patients of childbearing age are facing the trouble of fertility. For female kidney disease patients, the fetus has to grow in the mother's body for as long as 9 months. Coupled with the impact of pregnancy on kidney function, many female patients are daunted by the word "pregnancy". So, can female kidney disease patients complete the ten months of pregnancy and give birth to a healthy and lovely baby while taking care of their kidney disease? In fact, the question of whether kidney disease patients can become pregnant cannot be generalized. The key points to consider are three aspects: 1. To what extent has the kidney disease developed? 2. Is there hypertension? 3. The condition of kidney function.

Most kidney disease patients are allowed to become pregnant under appropriate circumstances, as follows:

0 1Acute nephritis

Symptoms include edema, hematuria, proteinuria and varying degrees of abnormal renal function. After treatment, these symptoms can disappear and renal function returns to normal. After acute nephritis is cured, it generally does not affect the fertility of female patients. It is recommended to get pregnant one year after acute nephritis is recovered.

0 2Chronic Glomerulonephritis

If the patient only has simple hematuria, or the 24-hour urine protein drops below 0.5 grams after treatment and lasts for more than half a year, and there is no hypertension or abnormal renal function, pregnancy can be considered. If the patient is still receiving drug treatment before planning pregnancy, the drug that may affect the growth and development of the fetus should be stopped, or the drug should be adjusted to other drugs that have no obvious effect on the growth and development of the fetus.

03****Nephrotic syndrome

Female patients with nephrotic syndrome with normal blood pressure and renal function may not be unable to get pregnant. However, pregnancy with nephrotic syndrome carries certain risks. Therefore, it is best for patients with nephrotic syndrome to undergo a renal puncture biopsy before planning a pregnancy, identify the pathological type, and receive treatment. It is safer to get pregnant after the condition improves.

04Lupus nephritis

Before planning a pregnancy, patients must fully communicate with their physicians and undergo a systematic evaluation of lupus nephritis and systemic lupus erythematosus. Pregnancy can only be considered when the following conditions are met: (1) no major organ involvement and the condition has been stable for more than six months; (2) the daily dose of prednisone is less than 10 mg, and all immunosuppressants that are prohibited during pregnancy have been discontinued for more than six months;

Pregnancy is an additional burden for patients with chronic kidney disease, which may affect the natural course of chronic kidney disease through various mechanisms. Women with chronic kidney disease should not try to have children under the following circumstances, otherwise, not only will the fetal survival rate be low, but the mother's kidney disease will also be aggravated, and even life-threatening to the expectant mother.

01Active chronic kidney disease

Pregnancy can cause kidney disease to persist or even worsen, with a sharp decline in kidney function. Exacerbation of kidney disease, such as severe hypertension and kidney function decline, can in turn make pregnancy impossible and force termination.

02Kidney disease patients have hypertension

Blood pressure is one of the key factors that determine whether patients with chronic kidney disease can become pregnant. On the one hand, patients with high blood pressure before pregnancy may have higher blood pressure after pregnancy, making it impossible to continue the pregnancy. The choice of antihypertensive drugs during pregnancy is limited, making the treatment of hypertension more difficult. On the other hand, high blood pressure is also an important factor in the aggravation of kidney disease, and irreversible deterioration of renal function may occur.

03Chronic renal insufficiency

After pregnancy, women with renal insufficiency, especially those with blood creatinine higher than 132.6 μmol/L, will have a significant decrease in the compensatory capacity of the kidneys. They will be unable to withstand the high blood volume during pregnancy and are prone to irreversible deterioration of renal function, or even uremia, and need to receive renal replacement therapy in advance. After pregnancy, the incidence of pregnancy-induced hypertension syndrome in patients with chronic renal insufficiency is significantly higher than that of normal women, and pregnant women are prone to preeclampsia or eclampsia. In addition, the prognosis for the baby is also poor, and premature birth may be a better outcome. In addition to premature birth, the incidence of intrauterine growth retardation and intrauterine fetal death is significantly increased.

In short, female kidney patients who are planning to get pregnant must fully communicate with their doctors before preparing for pregnancy. Female kidney patients who are not planning to get pregnant or are not suitable for pregnancy are advised to strictly take contraceptive measures. It is best not to use oral contraceptives, and condoms are recommended for contraception. Oral contraceptives may increase the risk of disease activity and the risk of thromboembolism.